Key PointsQuestionWhat advances in diagnosis and treatment of acute respiratory distress syndrome (ARDS) have been introduced in the last 5 years? FindingsThe diagnosis of ARDS is based on fulfilling the Berlin definition criteria for timing of the syndrome’s onset, origin of edema, chest radiograph findings, and hypoxemia. Few pharmacologic treatments are available and management remains supportive largely based on physiological approaches to lung-protective mechanical ventilation. MeaningThe Berlin definition of ARDS addressed limitations from prior definitions but poor reliability of some criteria may contribute to underrecognition. Clinical guidelines can assist clinicians in the evidence-based use of 6 interventions related to mechanical ventilation and extracorporeal membrane oxygenation.
JAMA – American Medical Association
Published: Feb 20, 2018
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