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B. Mukherji, A. Yagoda, H. Oettgen, I. Krakoff (1971)
Cyclic chemotherapy in lymphomaCancer, 28
H. Sahebjami, C. Vassallo (1975)
Rapidly Progressive Lymphoma of the Lung Appearing as the Adult Respiratory Distress SyndromeChest, 68
L. Robbins (1953)
The roentgenological appearance of parenchymal involvement of the lung by malignant lymphomaCancer, 6
S. Rosenberg, H. Diamond, B. Jaslowitz, L. Craver (1961)
LYMPHOSARCOMA: A REVIEW OF 1269 CASESMedicine, 40
D. Tierney (1972)
Surfactant secretion and respiratory distress syndromes.Annals of internal medicine, 77 4
POSTMORTEM evidence of pulmonary involvement was found in 40% of patients with malignant lymphoma.1 During the course of the disease, approximately 7% of the patients showed hilar lymphadenopathy. Pulmonary parenchymal infiltration is rare.2 A clinical syndrome directly related to pulmonary infiltration was described in a few single cases as a terminal event of a rapidly progressive disease.3 In this report, we describe three patients in whom an acute respiratory distress syndrome was the presenting symptom of malignant lymphoma. Report of Cases Case 1.— A 72-year-old man had severe respiratory distress that had developed over the previous four days. On examination, there were tachypnea, cyanosis, and tachycardia, but no fever. Coarse crepitations and occasional rhonchi were audible over both lungs. There was no venous congestion, and the liver and the spleen were not enlarged. The left anterior cervical lymph nodes were enlarged. There was a necrotic area on
JAMA – American Medical Association
Published: May 18, 1979
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