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Acute Renal Failure Associated with Carbon Tetrachloride Intoxication

Acute Renal Failure Associated with Carbon Tetrachloride Intoxication DESPITE the widespread use of carbon tetrachloride as a cleaning solvent, acute renal failure secondary to intoxication with this agent is infrequent. Presumably, time of exposure, adequacy of ventilation, and frequency of use have some bearing on the development of poisoning. These contributing factors are relatively well recognized by all, but others of importance apparently are not, for there continues to be a low but significant incidence of this illness. Since 1955 we have encountered 19 cases of acute renal failure related to carbon tetrachloride exposure. Review of our data has revealed several interesting points. Some important clues to early diagnosis have become apparent, and public health aspects relative to exposure deserve re-emphasis. Findings The data from the 19 patients are summarized in Tables 1 and 2. Exposure—Inhalation was the predominant route of exposure. Only 2 patients drank carbon tetrachloride, one in an attempt to commit suicide. In the other http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Acute Renal Failure Associated with Carbon Tetrachloride Intoxication

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References (7)

Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1962.03050360089019c
Publisher site
See Article on Publisher Site

Abstract

DESPITE the widespread use of carbon tetrachloride as a cleaning solvent, acute renal failure secondary to intoxication with this agent is infrequent. Presumably, time of exposure, adequacy of ventilation, and frequency of use have some bearing on the development of poisoning. These contributing factors are relatively well recognized by all, but others of importance apparently are not, for there continues to be a low but significant incidence of this illness. Since 1955 we have encountered 19 cases of acute renal failure related to carbon tetrachloride exposure. Review of our data has revealed several interesting points. Some important clues to early diagnosis have become apparent, and public health aspects relative to exposure deserve re-emphasis. Findings The data from the 19 patients are summarized in Tables 1 and 2. Exposure—Inhalation was the predominant route of exposure. Only 2 patients drank carbon tetrachloride, one in an attempt to commit suicide. In the other

Journal

JAMA – American Medical Association

Published: Sep 8, 1962

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