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Acute Generalized Bullous Eruption in a 2-Year-Old Boy—Quiz Case

Acute Generalized Bullous Eruption in a 2-Year-Old Boy—Quiz Case Report of a case A 2-year-old boy was admitted with an acute onset of generalized bullae. Before hospitalization, he had developed generalized erythema, become lethargic, and had an episode of vomiting and diarrhea. Within 2 hours, tense bullae had appeared, mostly on his head, neck, arms, and trunk. His only medication at the time of admission was dextromethorphan, for an upper respiratory tract infection. The findings of his medical history were unremarkable, except for occasional urticaria, which worsened with heat exposure. Physical examination revealed clusters of tense hemorrhagic bullae on the scalp, forehead, chest, back, umbilicus, and perineum (Figure 1). A punch biopsy specimen from one of the bullae was sent for histologic examination (Figure 2 and Figure 3), and a punch biopsy specimen of perilesional skin was sent for direct immunofluorescence. Figure 1. View LargeDownload Figure 2. View LargeDownload Figure 3. View LargeDownload http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Acute Generalized Bullous Eruption in a 2-Year-Old Boy—Quiz Case

Acute Generalized Bullous Eruption in a 2-Year-Old Boy—Quiz Case

Abstract

Report of a case A 2-year-old boy was admitted with an acute onset of generalized bullae. Before hospitalization, he had developed generalized erythema, become lethargic, and had an episode of vomiting and diarrhea. Within 2 hours, tense bullae had appeared, mostly on his head, neck, arms, and trunk. His only medication at the time of admission was dextromethorphan, for an upper respiratory tract infection. The findings of his medical history were unremarkable, except for occasional...
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Publisher
American Medical Association
Copyright
Copyright © 2008 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.144.5.673-d
Publisher site
See Article on Publisher Site

Abstract

Report of a case A 2-year-old boy was admitted with an acute onset of generalized bullae. Before hospitalization, he had developed generalized erythema, become lethargic, and had an episode of vomiting and diarrhea. Within 2 hours, tense bullae had appeared, mostly on his head, neck, arms, and trunk. His only medication at the time of admission was dextromethorphan, for an upper respiratory tract infection. The findings of his medical history were unremarkable, except for occasional urticaria, which worsened with heat exposure. Physical examination revealed clusters of tense hemorrhagic bullae on the scalp, forehead, chest, back, umbilicus, and perineum (Figure 1). A punch biopsy specimen from one of the bullae was sent for histologic examination (Figure 2 and Figure 3), and a punch biopsy specimen of perilesional skin was sent for direct immunofluorescence. Figure 1. View LargeDownload Figure 2. View LargeDownload Figure 3. View LargeDownload

Journal

Archives of DermatologyAmerican Medical Association

Published: May 1, 2008

Keywords: exanthema

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