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Acute Blindness in Early Syphilis

Acute Blindness in Early Syphilis Abstract A 46-year-old previously healthy man awoke with a profound loss of vision in the left eye. Shortly thereafter, he developed a generalized skin rash. Examination revealed the findings of a combined occlusion of central retinal vein and artery in the left eye, with cutaneous lesions resembling acute erythema nodosum. The cause was proven to be early infectious (secondary) syphilis, and strongly reactive Treponema pallidum immobilization and fluorescent treponemal antibody absorption (FTA-ABS) tests were found in both peripheral blood and aqueous humor of the involved eye. A treponemal organism was found by silver stain in the aqueous humor by Prof Pierre Collart five months after the patient had received a course of 12,000,000 units of parenteral penicillin. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Acute Blindness in Early Syphilis

Smith, J. Lawton
Archives of Ophthalmology , Volume 90 (3) – Sep 1, 1973
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Publisher
American Medical Association
Copyright
Copyright © 1973 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1973.01000050258015
Publisher site
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Abstract

Abstract A 46-year-old previously healthy man awoke with a profound loss of vision in the left eye. Shortly thereafter, he developed a generalized skin rash. Examination revealed the findings of a combined occlusion of central retinal vein and artery in the left eye, with cutaneous lesions resembling acute erythema nodosum. The cause was proven to be early infectious (secondary) syphilis, and strongly reactive Treponema pallidum immobilization and fluorescent treponemal antibody absorption (FTA-ABS) tests were found in both peripheral blood and aqueous humor of the involved eye. A treponemal organism was found by silver stain in the aqueous humor by Prof Pierre Collart five months after the patient had received a course of 12,000,000 units of parenteral penicillin.

Journal

Archives of Ophthalmology – American Medical Association

Published: Sep 1, 1973

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