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Acute Athetosis as a Result of Phenytoin Toxicity in a Child

Acute Athetosis as a Result of Phenytoin Toxicity in a Child Abstract • A case of acute athetosis in a child was found to be related to phenytoin toxicity. Symptoms were intermittent and coincided with drug administration. More common toxic effects were not noted on initial evaluation of the patient. (Am J Dis Child 130:75-76, 1976) References 1. Livingston S: Comprehensive Management of Epilepsy in Infancy, Childhood, and Adolescence . Springfield, Ill, Charles C Thomas Publisher 1972, pp 201-217. 2. Patel H, Crichton JU: The neurologic hazards of diphenylhydantoin in childhood . J Pediatr 73:676-684, 1968.Crossref 3. Kooiker JC, Sumi SM: Movement disorder as a manifestation of diphenylhydantoin intoxication . Neurology 24:68-71, 1974.Crossref 4. Logan WJ, Freeman JM: Pseudodegenerative disease due to diphenylhydantoin intoxication . Arch Neurol 21:631-637, 1969.Crossref 5. Gerber N, Lynn R, Oates J: Acute intoxication with 5,5-diphenylhydantoin (Dilantin) associated with impairment of biotransformation . Ann Intern Med 77:765-771, 1972.Crossref 6. Peters HA, Eichman PL, Price JM, et al: Abnormal copper and tryptophan metabolism and chelation therapy in anticonvulsant drug intolerance . Dis Nerv Syst 28:97-107, 1966. 7. Ausmar J: New developments in anticonvulsant therapy . Postgrad Med 47:122-127, 1970. 8. Stanbury JB, Wyngaarden JB, Fredrickson DS: The Metabolic Basis of Inherited Disease , ed 3. New York, McGraw-Hill Book Co Inc, 1972, pp 382, 436, 1486. 9. Goodman L, Gilman A: The Pharmacological Basis of Therapeutics , ed 3. Toronto, Macmillian Co, 1965, pp 225-226. 10. Grollman A, Grollman E: Pharmacology and Therapeutics , ed 7. Philadelphia, Lea & Febiger 1970, pp 187-188. 11. Kutt H, Penry JK: Usefulness of blood levels of antiepileptic drugs . Arch Neurol 31:283-288, 1974.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Diseases of Children American Medical Association

Acute Athetosis as a Result of Phenytoin Toxicity in a Child

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References (12)

Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0002-922X
DOI
10.1001/archpedi.1976.02120020077015
Publisher site
See Article on Publisher Site

Abstract

Abstract • A case of acute athetosis in a child was found to be related to phenytoin toxicity. Symptoms were intermittent and coincided with drug administration. More common toxic effects were not noted on initial evaluation of the patient. (Am J Dis Child 130:75-76, 1976) References 1. Livingston S: Comprehensive Management of Epilepsy in Infancy, Childhood, and Adolescence . Springfield, Ill, Charles C Thomas Publisher 1972, pp 201-217. 2. Patel H, Crichton JU: The neurologic hazards of diphenylhydantoin in childhood . J Pediatr 73:676-684, 1968.Crossref 3. Kooiker JC, Sumi SM: Movement disorder as a manifestation of diphenylhydantoin intoxication . Neurology 24:68-71, 1974.Crossref 4. Logan WJ, Freeman JM: Pseudodegenerative disease due to diphenylhydantoin intoxication . Arch Neurol 21:631-637, 1969.Crossref 5. Gerber N, Lynn R, Oates J: Acute intoxication with 5,5-diphenylhydantoin (Dilantin) associated with impairment of biotransformation . Ann Intern Med 77:765-771, 1972.Crossref 6. Peters HA, Eichman PL, Price JM, et al: Abnormal copper and tryptophan metabolism and chelation therapy in anticonvulsant drug intolerance . Dis Nerv Syst 28:97-107, 1966. 7. Ausmar J: New developments in anticonvulsant therapy . Postgrad Med 47:122-127, 1970. 8. Stanbury JB, Wyngaarden JB, Fredrickson DS: The Metabolic Basis of Inherited Disease , ed 3. New York, McGraw-Hill Book Co Inc, 1972, pp 382, 436, 1486. 9. Goodman L, Gilman A: The Pharmacological Basis of Therapeutics , ed 3. Toronto, Macmillian Co, 1965, pp 225-226. 10. Grollman A, Grollman E: Pharmacology and Therapeutics , ed 7. Philadelphia, Lea & Febiger 1970, pp 187-188. 11. Kutt H, Penry JK: Usefulness of blood levels of antiepileptic drugs . Arch Neurol 31:283-288, 1974.Crossref

Journal

American Journal of Diseases of ChildrenAmerican Medical Association

Published: Jan 1, 1976

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