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Acquired Immunodeficiency Syndrome and the Eye-Reply

Acquired Immunodeficiency Syndrome and the Eye-Reply Abstract In reply Dr Brein asks 2 important questions. The first is the frequency with which individuals with human immunodeficiency virus infection should receive ophthalmologic examinations. For patients with known cytomegalovirus (CMV) retinitis, many experienced clinicians recommend monthly follow-up visits. Approximately 1 month is required after the initiation of therapy for the lesions to appear quiet,1 and approximately 1 month is required for the lesion borders to move a clinically recognizable distance. Hence, monthly follow-up visits seem to be reasonable. Some experts will have an additional visit 2 weeks after the initiation of the therapy. The purposes of this visit are to confirm the diagnosis and to confirm that the lesions are not worsening after initial therapy. For patients treated with the ganciclovir intraocular device, typical postoperative follow-up visits are used initially (ie, at 1 day, 1 week, and then 1 month after surgery). Regardless of the form of therapy, References 1. Jabs DA. Ocular manifestations of HIV infection . Trans Am Ophthalmol Soc . 1995;93:623-683. 2. Pertel P, Hirschtick R, Phair J, Chmiel J, Poggensee L, Murphy R. Risk of developing cytomegalovirus retinitis in persons infected with the human immunodeficiency virus . J Acquir Immune Defic Syndr Hum Retrovirol . 1992;5:1069-1074. 3. Gallant JE, Moore RD, Richman DD, Keruly J, Chaisson RE, and the Zidovudine Epidemiology Study Group. Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine . J Infect Dis . 1992;166:1223-1227.Crossref 4. Hoover DR, Peng Y, Saah A, et al. Occurrence of cytomegalovirus retinitis after human immunodeficiency virus immunosuppression . Arch Ophthalmol . 1996;114:821-827.Crossref 5. Kuppermann BD, Petty JG, Richman DD, et al. Correlation between CD4+ counts and prevalence of cytomegalovirus retinitis and human immunodeficiency virus—related noninfectious retinal vasculopathy in patients with acquired immunodeficiency syndrome . Am] Ophthalmol . 1993;115:575-582. 6. Baldassano V, Dunn JP, Feinberg J, Jabs DA. Cytomegalovirus retinitis and low CD4+ T-lymphocyte counts . N Engl J Med . 1995;333:670.Crossref 7. Kitahata MM, Koepsell TD, Deyo RA, Maxwell CL, Dodge WT, Wagner EH. Physicians' experience with the acquired immunodeficiency syndrome as a factor in patient's survival . N Engl J Med . 1996;334:701-706.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Acquired Immunodeficiency Syndrome and the Eye-Reply

Archives of Ophthalmology , Volume 115 (2) – Feb 1, 1997

Acquired Immunodeficiency Syndrome and the Eye-Reply

Abstract

Abstract In reply Dr Brein asks 2 important questions. The first is the frequency with which individuals with human immunodeficiency virus infection should receive ophthalmologic examinations. For patients with known cytomegalovirus (CMV) retinitis, many experienced clinicians recommend monthly follow-up visits. Approximately 1 month is required after the initiation of therapy for the lesions to appear quiet,1 and approximately 1 month is required for the lesion borders to move a clinically...
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Publisher
American Medical Association
Copyright
Copyright © 1997 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1997.01100150294034
Publisher site
See Article on Publisher Site

Abstract

Abstract In reply Dr Brein asks 2 important questions. The first is the frequency with which individuals with human immunodeficiency virus infection should receive ophthalmologic examinations. For patients with known cytomegalovirus (CMV) retinitis, many experienced clinicians recommend monthly follow-up visits. Approximately 1 month is required after the initiation of therapy for the lesions to appear quiet,1 and approximately 1 month is required for the lesion borders to move a clinically recognizable distance. Hence, monthly follow-up visits seem to be reasonable. Some experts will have an additional visit 2 weeks after the initiation of the therapy. The purposes of this visit are to confirm the diagnosis and to confirm that the lesions are not worsening after initial therapy. For patients treated with the ganciclovir intraocular device, typical postoperative follow-up visits are used initially (ie, at 1 day, 1 week, and then 1 month after surgery). Regardless of the form of therapy, References 1. Jabs DA. Ocular manifestations of HIV infection . Trans Am Ophthalmol Soc . 1995;93:623-683. 2. Pertel P, Hirschtick R, Phair J, Chmiel J, Poggensee L, Murphy R. Risk of developing cytomegalovirus retinitis in persons infected with the human immunodeficiency virus . J Acquir Immune Defic Syndr Hum Retrovirol . 1992;5:1069-1074. 3. Gallant JE, Moore RD, Richman DD, Keruly J, Chaisson RE, and the Zidovudine Epidemiology Study Group. Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine . J Infect Dis . 1992;166:1223-1227.Crossref 4. Hoover DR, Peng Y, Saah A, et al. Occurrence of cytomegalovirus retinitis after human immunodeficiency virus immunosuppression . Arch Ophthalmol . 1996;114:821-827.Crossref 5. Kuppermann BD, Petty JG, Richman DD, et al. Correlation between CD4+ counts and prevalence of cytomegalovirus retinitis and human immunodeficiency virus—related noninfectious retinal vasculopathy in patients with acquired immunodeficiency syndrome . Am] Ophthalmol . 1993;115:575-582. 6. Baldassano V, Dunn JP, Feinberg J, Jabs DA. Cytomegalovirus retinitis and low CD4+ T-lymphocyte counts . N Engl J Med . 1995;333:670.Crossref 7. Kitahata MM, Koepsell TD, Deyo RA, Maxwell CL, Dodge WT, Wagner EH. Physicians' experience with the acquired immunodeficiency syndrome as a factor in patient's survival . N Engl J Med . 1996;334:701-706.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Feb 1, 1997

References