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Accuracy of Cholesterol Measurements-Reply

Accuracy of Cholesterol Measurements-Reply Abstract In Reply.— It has been appropriately pointed out by Bock that a 5% deviation from "true" value may be too restrictive, especially when only one or two samples are being evaluated at a reference and at a clinical laboratory. The value of 9.5% recommended by the National Cholesterol Education Program is perhaps more practical and allows for each laboratory to be within 5% of the target value. We used the 5% figure in the editorial1 because we believed that if a series of cross-checked samples is consistently more than 5% off of the true value (Centers for Disease Control laboratory value), then something is wrong in the laboratory being evaluated. We appreciate Bock's comments on this point. References 1. Dujovne CA, Harris WS. Variabilities in serum lipid measurements: do they impede proper diagnosis and treatment of dyslipidemias? Arch Intern Med . 1990;150:1583-1585.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Accuracy of Cholesterol Measurements-Reply

Accuracy of Cholesterol Measurements-Reply

Abstract

Abstract In Reply.— It has been appropriately pointed out by Bock that a 5% deviation from "true" value may be too restrictive, especially when only one or two samples are being evaluated at a reference and at a clinical laboratory. The value of 9.5% recommended by the National Cholesterol Education Program is perhaps more practical and allows for each laboratory to be within 5% of the target value. We used the 5% figure in the editorial1 because we believed that if a series...
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Publisher
American Medical Association
Copyright
Copyright © 1991 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1991.00400080155043
Publisher site
See Article on Publisher Site

Abstract

Abstract In Reply.— It has been appropriately pointed out by Bock that a 5% deviation from "true" value may be too restrictive, especially when only one or two samples are being evaluated at a reference and at a clinical laboratory. The value of 9.5% recommended by the National Cholesterol Education Program is perhaps more practical and allows for each laboratory to be within 5% of the target value. We used the 5% figure in the editorial1 because we believed that if a series of cross-checked samples is consistently more than 5% off of the true value (Centers for Disease Control laboratory value), then something is wrong in the laboratory being evaluated. We appreciate Bock's comments on this point. References 1. Dujovne CA, Harris WS. Variabilities in serum lipid measurements: do they impede proper diagnosis and treatment of dyslipidemias? Arch Intern Med . 1990;150:1583-1585.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Aug 1, 1991

References