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Accuracy and Reliability of Eye-Based vs Quadrant-Based Diagnosis of Plus Disease in Retinopathy of Prematurity

Accuracy and Reliability of Eye-Based vs Quadrant-Based Diagnosis of Plus Disease in Retinopathy... Key PointsQuestionIs plus disease in retinopathy of prematurity more reliably and accurately diagnosed by eye-based assessment of overall retinal appearance or by quadrant-based assessment combining grades of individual quadrants? FindingsIn this multicenter cohort study including 141 preterm infants, graders diagnosed 197 eyes by reviewing the entire wide-angle retinal images (eye-based diagnosis; plus vs not plus) and subsequently by reviewing each of the cropped quadrant images (plus vs not plus), which was combined into a quadrant-based diagnosis. Graders had lower intragrader and intergrader agreement and agreement with reference standard diagnosis using quadrant-based diagnosis than eye-based diagnosis. MeaningEye-based diagnosis may have advantages over quadrant-based diagnosis regarding reliability and accuracy. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Ophthalmology American Medical Association

Accuracy and Reliability of Eye-Based vs Quadrant-Based Diagnosis of Plus Disease in Retinopathy of Prematurity

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Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
2168-6165
eISSN
2168-6173
DOI
10.1001/jamaophthalmol.2018.1195
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionIs plus disease in retinopathy of prematurity more reliably and accurately diagnosed by eye-based assessment of overall retinal appearance or by quadrant-based assessment combining grades of individual quadrants? FindingsIn this multicenter cohort study including 141 preterm infants, graders diagnosed 197 eyes by reviewing the entire wide-angle retinal images (eye-based diagnosis; plus vs not plus) and subsequently by reviewing each of the cropped quadrant images (plus vs not plus), which was combined into a quadrant-based diagnosis. Graders had lower intragrader and intergrader agreement and agreement with reference standard diagnosis using quadrant-based diagnosis than eye-based diagnosis. MeaningEye-based diagnosis may have advantages over quadrant-based diagnosis regarding reliability and accuracy.

Journal

JAMA OphthalmologyAmerican Medical Association

Published: Jun 26, 2018

References

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