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ABSTRACT OF PAPER FURTHER EFFORTS TO INFLUENCE X-RAY CATARACT BY CHEMICAL AGENTS

ABSTRACT OF PAPER FURTHER EFFORTS TO INFLUENCE X-RAY CATARACT BY CHEMICAL AGENTS Abstract LAST YEAR my co-workers and I reported in a preliminary study on the relation of cysteine treatment to x-ray damage of the rabbit's eye which had been exposed locally to a single dose of 1,500 r of penetrating x-rays. There was at this time strongly suggestive evidence that among the signs of radiation damage to the eye two characteristic late effects of such radiation, epilation and x-ray cataract, were partially prevented by the intravenous use of 2 gm. of cysteine prior to irradiation. These animals have been followed now over periods of 12 to 16 months. Total cataract has developed in the control group in 12 of 14 animals within the observation time of 14 months. None of the cysteine-pretreated eyes showed at this time a lenticular opacity which was dense enough or extensive enough to interfere substantially with the visibility of fundus details. However, all these lenses exhibited some http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Ophthalmology American Medical Association

ABSTRACT OF PAPER FURTHER EFFORTS TO INFLUENCE X-RAY CATARACT BY CHEMICAL AGENTS

A.M.A. Archives of Ophthalmology , Volume 47 (1) – Jan 1, 1952

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Publisher
American Medical Association
Copyright
Copyright © 1952 American Medical Association. All Rights Reserved.
ISSN
0096-6339
DOI
10.1001/archopht.1952.01700030024002
Publisher site
See Article on Publisher Site

Abstract

Abstract LAST YEAR my co-workers and I reported in a preliminary study on the relation of cysteine treatment to x-ray damage of the rabbit's eye which had been exposed locally to a single dose of 1,500 r of penetrating x-rays. There was at this time strongly suggestive evidence that among the signs of radiation damage to the eye two characteristic late effects of such radiation, epilation and x-ray cataract, were partially prevented by the intravenous use of 2 gm. of cysteine prior to irradiation. These animals have been followed now over periods of 12 to 16 months. Total cataract has developed in the control group in 12 of 14 animals within the observation time of 14 months. None of the cysteine-pretreated eyes showed at this time a lenticular opacity which was dense enough or extensive enough to interfere substantially with the visibility of fundus details. However, all these lenses exhibited some

Journal

A.M.A. Archives of OphthalmologyAmerican Medical Association

Published: Jan 1, 1952

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