Abstract In view of the great importance in the practice of medicine of an adequate understanding of the normal processes of absorption from the gastro-intestinal tract, one is rather surprised to find that many hiatuses exist in the knowledge of this function—hiatuses that involve rather basic considerations. This is particularly true with reference to the absorptive activities of the large bowel, concerning which comparatively few facts are known for certain and much of the experimental investigation of which is inconclusive. No one can question the ability of the large bowel to absorb certain substances, e. g., certain anesthetic substances, because of the characteristic train of symptoms which follow their administration and which could occur in no way other than as a result of absorption. Thus, one who has even once seen rectal anesthesia from ether or avertin has seen spectacular and incontrovertible evidence of specific colonic absorption. Unfortunately, however, from the References 1. Ebeling, W. W.: Absorption of Dextrose from the Colon , Arch. Surg. 26:134 ( (Jan.) ) 1933.Crossref 2. Tallermann, K. H.: On the Rectal Absorption of Glucose , Quart. J. Med. 13:356 ( (July) ) 1920.Crossref 3. Varela and Rubino: Rektale Dextrose Zufuhr und Blutzucker , Med. Klin. 18:831, 1922. 4. Franke, W., and Wagner, R. J.: Studies on the Fermentable Blood Sugar After Parenteral and Rectal Administration of Glucose , J. Metab. Research 6:375, 1924. 5. Levi, D.: A Note on the Glucose Enema and Its Value in Postoperative Treatment , Brit. J. Surg. 15:282, 1927.Crossref 6. Pressman, J. J.: Absorption of Glucose per Rectum , Am. J. M. Sc. 179:520, 1930.Crossref 7. de Takáts, G.: Push Fluids; Surgeon's Postoperative Order , Am. J. Surg. 11:39, 1931.Crossref 8. Scott, E. L., and Zweighaft, J. F. B.: Blood Sugar in Man Following the Rectal Administrations of Dextrose , Arch. Int. Med. 49:221 ( (Feb.) ) 1932.Crossref 9. Cori, C.: Mammalian Carbohydrate Metabolism , Physiol. Rev. 11:143, 1931. 10. Magee, H. E., and Reid, E.: Absorption of Glucose from the Alimentary Canal , J. Physiol. 73:163, 1931. 11. Hari, P., and Halasz, A. V.: Biochem. Ztschr. 88:337, 1918. 12. Carpenter, T. M.: Human Metabolism with Enemata of Alcohol Dextrose, and Levulose , Washington, D. C., Carnegie Institution, publ. 369, 1925. 13. Brodie, T. G.; Cullis, W. C., and Halliburton, W. D.: J. Physiol. 40:173, 1910. 14. Koster, H.: Collens, W. S., and Goldzieher, M. A.: Intravenous Injection of Glucose; Its Effect on Respiratory Quotient , Am. J. Surg. 8:970, 1930.Crossref 15. Deucher, P.: Deutsches Arch. f. klin. Med. 58:210, 1897. 16. Bingel, A.: Therap. d. Gegenw. 46:436, 1905. 17. Scott, E. L., and Zweighaft, J. F. B.: Blood Sugar in Man Following the Rectal Administration of Dextrose , Arch. Int. Med. 49:221 ( (Feb.) ) 1932.Crossref 18. McNealy, R. W., and Willems, J. D.: Absorption of Glucose from Colon; Preliminary Study of Glucose Enema , Surg., Gynec. & Obst. 49:794, 1929. 19. Bingel, A.: Therap. d. Gegenw. 46:436, 1905. 20. Boyd, F. D., and Robertson, T.: Scottish M. & S. J. 18:193, 1906. 21. Cori, C. F.: Fate of Sugar in Animal Body; Rate of Absorption of Hexoses and Pentoses from Intestinal Tract , J. Biol. Chem. 66:691, 1925.
Archives of Surgery – American Medical Association
Published: Oct 1, 1934