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ABSENCE OF TONSILS AS A FACTOR IN THE DEVELOPMENT OF BULBAR POLIOMYELITIS

ABSENCE OF TONSILS AS A FACTOR IN THE DEVELOPMENT OF BULBAR POLIOMYELITIS Foremost among the many unknowns in the pathogenesis of poliomyelitis are the factors that determine the type of response to the infection. There is ample evidence that infection with the poliomyelitis viruses is widespread, ultimately involving almost all persons, except those in isolated areas. In most of these persons, the infection is mild, producing no paralysis and usually occuring without recognizable symptoms. Yet a small number of persons respond badly to the virus invasion, with resultant paralysis. Of those with central nervous system involvement, a few show involvement of the vital medullary centers, while the majority show lesions of the spinal cord. The proportion with bulbar paralysis has supposedly increased in recent years and is greater in the older age groups. Very little evidence is currently available, however, as to the factors that determine this localization of the paralysis in the bulbar area. Among the many factors that have been http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

ABSENCE OF TONSILS AS A FACTOR IN THE DEVELOPMENT OF BULBAR POLIOMYELITIS

JAMA , Volume 155 (13) – Jul 24, 1954

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Publisher
American Medical Association
Copyright
Copyright © 1954 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1954.03690310001001
Publisher site
See Article on Publisher Site

Abstract

Foremost among the many unknowns in the pathogenesis of poliomyelitis are the factors that determine the type of response to the infection. There is ample evidence that infection with the poliomyelitis viruses is widespread, ultimately involving almost all persons, except those in isolated areas. In most of these persons, the infection is mild, producing no paralysis and usually occuring without recognizable symptoms. Yet a small number of persons respond badly to the virus invasion, with resultant paralysis. Of those with central nervous system involvement, a few show involvement of the vital medullary centers, while the majority show lesions of the spinal cord. The proportion with bulbar paralysis has supposedly increased in recent years and is greater in the older age groups. Very little evidence is currently available, however, as to the factors that determine this localization of the paralysis in the bulbar area. Among the many factors that have been

Journal

JAMAAmerican Medical Association

Published: Jul 24, 1954

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