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A Systematic Review of the Treatment of Scabies

A Systematic Review of the Treatment of Scabies dence interval 95% of the time. Finally, it can be in- clovir instead of placebo, 1 additional patient would be ferred that since the 95% confidence interval of the dif- totally healed by day 30. The probability that patients who ference in response rates excludes the zero difference, one are treated in your practice would fall outside of this range can reject the null hypothesis that the 2 treatments are is1in20. the same. The rejection of the null hypothesis in this case hasa1in20 chance of being wrong (P = .05). Michael Bigby, MD A busy clinician responsible for the care of patients Boston, Mass might ask “so what?” The most important information for the clinician is the response in the population at large 1. Bigby M, Gadenne AS. Understanding and evaluating clinical trials. J Am Acad and in his or her particular patient! Herein lies the power Dermatol. 1996;34:555-590. 2. Bigby M. Evidence-based medicine in a nutshell: a guide to finding and using of the confidence interval. The population or true re- the best evidence in caring for patients. Arch Dermatol. 1998;134:1609-1618. sponse to treatment will most likely lie near the middle 3. Sackett D, Richardson W, Rosenberg W, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Dermatology American Medical Association

A Systematic Review of the Treatment of Scabies

Bigby, Michael
JAMA Dermatology , Volume 136 (3) – Mar 1, 2000
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Publisher
American Medical Association
Copyright
Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6068
eISSN
2168-6084
DOI
10.1001/archderm.136.3.387
Publisher site
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Abstract

dence interval 95% of the time. Finally, it can be in- clovir instead of placebo, 1 additional patient would be ferred that since the 95% confidence interval of the dif- totally healed by day 30. The probability that patients who ference in response rates excludes the zero difference, one are treated in your practice would fall outside of this range can reject the null hypothesis that the 2 treatments are is1in20. the same. The rejection of the null hypothesis in this case hasa1in20 chance of being wrong (P = .05). Michael Bigby, MD A busy clinician responsible for the care of patients Boston, Mass might ask “so what?” The most important information for the clinician is the response in the population at large 1. Bigby M, Gadenne AS. Understanding and evaluating clinical trials. J Am Acad and in his or her particular patient! Herein lies the power Dermatol. 1996;34:555-590. 2. Bigby M. Evidence-based medicine in a nutshell: a guide to finding and using of the confidence interval. The population or true re- the best evidence in caring for patients. Arch Dermatol. 1998;134:1609-1618. sponse to treatment will most likely lie near the middle 3. Sackett D, Richardson W, Rosenberg W,

Journal

JAMA Dermatology – American Medical Association

Published: Mar 1, 2000

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