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Abstract REPORT OF A CASE A 58-year-old woman presented to her family physician with an asymptomatic red bump over her left cheek. The lesion started as a small papule and had grown in size at a relatively rapid rate over a period of one month. There was no history of preceding skin lesion at the site. The patient's medical history revealed that she had been hypertensive but adequately controlled with an antihypertensive medication. She denied any history of systemic complaints such as fever, weight loss, or malaise; her medical history was noncontributory.Physical examination disclosed a 1.3 × 1.2-cm erythematous and semifirm nodule on the left cheek (Fig 1). No other physical findings were noted. Due to the rapid onset of the lesion, the diagnosis of malignant lymphoid infiltrate was suspected and the patient was referred to a surgeon for an excisional biopsy.Hematoxylin-eosin-stained sections of the biopsy specimen exhibited a References 1. McNutt NS: Cutaneous lymphohistiocytic infiltrates simulating malignant lymphomas , in Murphy GF, Mihm MC Jr (eds): Lymphoproliferative Disorders of the Skin . Stoneham, Mass, Butterworths, 1986, pp 262-266. 2. Mopper C, Rogin JR: Benign solitary lymphocytoma . Arch Dermatol 1951;63:184-190. 3. Allen AC: Persistent 'insect bites' simulating lymphoblastomas, histiocytoses, and squamous cell carcinoma . Am J Pathol 1948;24:367-387. 4. Burg G, Braun-Falco O: Cutaneous Lymphoma, Pseudolymphomas and Related Disorders . New York, Springer-Verlag NY Inc, 1983. 5. MacDonald DM: Histopathological differentation of benign and malignant cutaneous lymphocytic infiltrates . Br J Dermatol 1982;107:715-718.Crossref 6. Rauch HJ, Kerl H, Kresbach H: Detection of cytoplasmic immunoglobulin in malignant lymphomas and pseudolymphomas . J Invest Dermatol 1981;76:418.
Archives of Dermatology – American Medical Association
Published: Aug 1, 1988
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