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A Solitary Neurofibroma on the Finger

A Solitary Neurofibroma on the Finger Abstract To the Editor.— Neurofibromas may present as multiple lesions as in von Recklinghausen's disease or as solitary cutaneous lesions. Clinically, both types appear as smooth, polypoid, soft or firm, flesh-colored lesions that may vary in size, the larger lesions being pedunculated.1 When neurofibromas present as solitary cutaneous lesions they are not associated with cafe au lait spots or a family history of von Recklinghausen's disease.2 Report of a Case.— A 40-year-old woman noted a lesion growing on her finger over a period of one year. The lesion had increased in size over the last six months following the application of an antiwart medication.On physical examination, the third digit of the left hand presented a 6 × 8-mm dome-shaped, pedunculated, nontender, soft nodule with a violaceous hue (Fig 1). The patient had no cafe au lait spots, axillary freckling, diffuse pigmentation of skin, scoliosis References 1. From L, Assaad D: Neoplasms and hyperplasias of neural and muscular origin , in Fitzpatrick TB, Eisen AZ, Wolff K, et al (eds): Dermatology in General Medicine , ed 3. New York, McGraw-Hill International Book Co, 1987, pp 1054-1055. 2. Winkelmann RK, Johnson LA: Cholinesterases in neurofibromas . Arch Dermatol 1962;85:106-114.Crossref 3. Hawkin JC, Reed RJ: Tumors of the Peripheral Nervous System . Atlas of Tumor Pathology, Armed Forces Institute of Pathology, 1969, section 2 , pt (3) , pp 67-106. 4. Carter DM, O'Keefe IJ: Hereditary cutaneous disorders , in Moschella SL, Huley HJ (eds): Dermatology , ed 2. Philadelphia, WB Saunders Co, 1985, p 1193. 5. Enzinger FM, Weiss SW: Benign tumors of peripheral nerves , in Soft Tissue Tumors . St Louis, CV Mosby Co, 1983, pp 580-624. 6. Stefansson K, Wollmann R, Jerkovic M: S-100 protein in soft-tissue tumors derived from Schwann cells and melanocytes . Am J Pathol 1982;106:261-268. 7. Riccardi VM, Eichner JE: Neurofibromatosis Phenotype, Natural History and Pathogenesis . Baltimore, The Johns Hopkins University Press, 1986, pp 36-39. 8. Hajdu SI, Hajdu EM: Differential Diagnosis of Soft Tissue and Bone Tumors . Philadelphia, Lea & Febiger, 1986, p 58. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

A Solitary Neurofibroma on the Finger

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Publisher
American Medical Association
Copyright
Copyright © 1988 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1988.01670080011006
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— Neurofibromas may present as multiple lesions as in von Recklinghausen's disease or as solitary cutaneous lesions. Clinically, both types appear as smooth, polypoid, soft or firm, flesh-colored lesions that may vary in size, the larger lesions being pedunculated.1 When neurofibromas present as solitary cutaneous lesions they are not associated with cafe au lait spots or a family history of von Recklinghausen's disease.2 Report of a Case.— A 40-year-old woman noted a lesion growing on her finger over a period of one year. The lesion had increased in size over the last six months following the application of an antiwart medication.On physical examination, the third digit of the left hand presented a 6 × 8-mm dome-shaped, pedunculated, nontender, soft nodule with a violaceous hue (Fig 1). The patient had no cafe au lait spots, axillary freckling, diffuse pigmentation of skin, scoliosis References 1. From L, Assaad D: Neoplasms and hyperplasias of neural and muscular origin , in Fitzpatrick TB, Eisen AZ, Wolff K, et al (eds): Dermatology in General Medicine , ed 3. New York, McGraw-Hill International Book Co, 1987, pp 1054-1055. 2. Winkelmann RK, Johnson LA: Cholinesterases in neurofibromas . Arch Dermatol 1962;85:106-114.Crossref 3. Hawkin JC, Reed RJ: Tumors of the Peripheral Nervous System . Atlas of Tumor Pathology, Armed Forces Institute of Pathology, 1969, section 2 , pt (3) , pp 67-106. 4. Carter DM, O'Keefe IJ: Hereditary cutaneous disorders , in Moschella SL, Huley HJ (eds): Dermatology , ed 2. Philadelphia, WB Saunders Co, 1985, p 1193. 5. Enzinger FM, Weiss SW: Benign tumors of peripheral nerves , in Soft Tissue Tumors . St Louis, CV Mosby Co, 1983, pp 580-624. 6. Stefansson K, Wollmann R, Jerkovic M: S-100 protein in soft-tissue tumors derived from Schwann cells and melanocytes . Am J Pathol 1982;106:261-268. 7. Riccardi VM, Eichner JE: Neurofibromatosis Phenotype, Natural History and Pathogenesis . Baltimore, The Johns Hopkins University Press, 1986, pp 36-39. 8. Hajdu SI, Hajdu EM: Differential Diagnosis of Soft Tissue and Bone Tumors . Philadelphia, Lea & Febiger, 1986, p 58.

Journal

Archives of DermatologyAmerican Medical Association

Published: Aug 1, 1988

References