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A Solitary, Erythematous, Hyperkeratotic Papule

A Solitary, Erythematous, Hyperkeratotic Papule Abstract REPORT OF A CASE A 39-year-old white woman presented complaining of a pruritic lesion on her lower abdomen. It had not changed significantly since she noted it 6 months previously. It would occasionally crust over and was intermittently pruritic.Her medical and family history and a review of systems were unremarkable.Cutaneous examination revealed a single 3-mm, wellcircumscribed, erythematous papule with central umbilication on the left lower abdomen just above the belt line (Figure 1). There were no other skin, nail, or mucosal findings.A shave biopsy specimen of the lesion revealed hyperkeratosis, extensive suprabasalar acantholysis, and a superficial dermal round cell infiltrate (Figure 2 and Figure 3).What is your diagnosis? DIAGNOSIS: Acantholytic acanthoma. DISCUSSION The solitary acantholytic acanthoma is a benign cutaneous tumor probably seen much more commonly than is reported. First described by Brownstein1 in 1985, his review of 31 References 1. Brownstein MH. The benign acanthoma . J Cutan Pathol. 1985;12:172-188.Crossref 2. Brownstein MH. Acantholytic acanthoma . J Am Acad Dermatol. 1988;19:783-786.Crossref 3. Ackerman AB. Focal acantholytic dyskeratosis . Arch Dermatol. 1972;106:702-706.Crossref 4. Chorzelski TP, Kudejko J, Jablonska S. Is papular acantholytic dyskeratosis of the vulva a new entity? Am J Dermatopathol. 1984;6:557-560.Crossref 5. Coppola 0. Papular acantholytic dyskeratosis . Am J Dermatopathol. 1986;8: 364-365.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

A Solitary, Erythematous, Hyperkeratotic Papule

Archives of Dermatology , Volume 131 (2) – Feb 1, 1995

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Publisher
American Medical Association
Copyright
Copyright © 1995 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1995.01690140097017
Publisher site
See Article on Publisher Site

Abstract

Abstract REPORT OF A CASE A 39-year-old white woman presented complaining of a pruritic lesion on her lower abdomen. It had not changed significantly since she noted it 6 months previously. It would occasionally crust over and was intermittently pruritic.Her medical and family history and a review of systems were unremarkable.Cutaneous examination revealed a single 3-mm, wellcircumscribed, erythematous papule with central umbilication on the left lower abdomen just above the belt line (Figure 1). There were no other skin, nail, or mucosal findings.A shave biopsy specimen of the lesion revealed hyperkeratosis, extensive suprabasalar acantholysis, and a superficial dermal round cell infiltrate (Figure 2 and Figure 3).What is your diagnosis? DIAGNOSIS: Acantholytic acanthoma. DISCUSSION The solitary acantholytic acanthoma is a benign cutaneous tumor probably seen much more commonly than is reported. First described by Brownstein1 in 1985, his review of 31 References 1. Brownstein MH. The benign acanthoma . J Cutan Pathol. 1985;12:172-188.Crossref 2. Brownstein MH. Acantholytic acanthoma . J Am Acad Dermatol. 1988;19:783-786.Crossref 3. Ackerman AB. Focal acantholytic dyskeratosis . Arch Dermatol. 1972;106:702-706.Crossref 4. Chorzelski TP, Kudejko J, Jablonska S. Is papular acantholytic dyskeratosis of the vulva a new entity? Am J Dermatopathol. 1984;6:557-560.Crossref 5. Coppola 0. Papular acantholytic dyskeratosis . Am J Dermatopathol. 1986;8: 364-365.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Feb 1, 1995

References