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A REVIEW AND CLASSIFICATION OF BONE SARCOMAS

A REVIEW AND CLASSIFICATION OF BONE SARCOMAS Abstract The knowledge of tumors of bone and bone marrow is still in the descriptive stage. To reach a correct histologic diagnosis of the case and to provide some conception of the probable clinical course are all that can be expected at the present time, and often more than is accomplished. The separation of the numerous tumors of this group into well-defined clinical and pathologic entities is far from complete, while knowledge of the exact origins of these tumors and of their various exciting and contributing causative factors is extremely fragmentary, or, indeed, wholly lacking. Moreover, with the present trend of medical research, the prospects are not favorable to important progress in this field. Serology, immunology, chemistry, studies in nutrition, and the use of modern instruments of precision have contributed little and promise little in the study of bone tumors. Abundant clinical material, wide clinical experience, and knowledge of the embryology, References 1. Wallgren: Virchows Arch. f. path. Anat. 232:381, 1921.Crossref 2. Symmers, D., and Vance, M.: Am. J. M. Sc. 152:23 ( (July) ) 1916.Crossref 3. Howard and Crile: Ann. Surg. 42:358, 1905.Crossref 4. Martland, H. S.: Proc. New York Path. Soc. 21:102, 1921. 5. Ewing, James: Neoplastic Diseases , Ed. 2, Philadelphia, W. B. Saunders Company, 1922, pp. 294-295. 6. Ribbert: Centralbl. f. Path. 15:337, 1904. 7. Norris: Proc. New York Path. Soc. N. S. 6:128, 1906. 8. Since this article was written, I have obtained all the data in a case demonstrating the transformation of a benign giant cell tumor of the tibia into a malignant large spindle cell sarcoma as a result of repeated curettage, infection and radium treatment, and terminating, after amputation, in death from pulmonary metastases. This case will be fully reported later. 9. Jungling: Strahlentherapie 12:178, 1921. 10. Jeanbreau and Riche: Rev. de chir. 32:153, 1905. 11. Goebel: Arch. f. klin. chir. 87:191, 1908. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

A REVIEW AND CLASSIFICATION OF BONE SARCOMAS

EWING, JAMES
Archives of Surgery , Volume 4 (3) – May 1, 1922
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Publisher
American Medical Association
Copyright
Copyright © 1922 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1922.01110120002001
Publisher site
See Article on Publisher Site

Abstract

Abstract The knowledge of tumors of bone and bone marrow is still in the descriptive stage. To reach a correct histologic diagnosis of the case and to provide some conception of the probable clinical course are all that can be expected at the present time, and often more than is accomplished. The separation of the numerous tumors of this group into well-defined clinical and pathologic entities is far from complete, while knowledge of the exact origins of these tumors and of their various exciting and contributing causative factors is extremely fragmentary, or, indeed, wholly lacking. Moreover, with the present trend of medical research, the prospects are not favorable to important progress in this field. Serology, immunology, chemistry, studies in nutrition, and the use of modern instruments of precision have contributed little and promise little in the study of bone tumors. Abundant clinical material, wide clinical experience, and knowledge of the embryology, References 1. Wallgren: Virchows Arch. f. path. Anat. 232:381, 1921.Crossref 2. Symmers, D., and Vance, M.: Am. J. M. Sc. 152:23 ( (July) ) 1916.Crossref 3. Howard and Crile: Ann. Surg. 42:358, 1905.Crossref 4. Martland, H. S.: Proc. New York Path. Soc. 21:102, 1921. 5. Ewing, James: Neoplastic Diseases , Ed. 2, Philadelphia, W. B. Saunders Company, 1922, pp. 294-295. 6. Ribbert: Centralbl. f. Path. 15:337, 1904. 7. Norris: Proc. New York Path. Soc. N. S. 6:128, 1906. 8. Since this article was written, I have obtained all the data in a case demonstrating the transformation of a benign giant cell tumor of the tibia into a malignant large spindle cell sarcoma as a result of repeated curettage, infection and radium treatment, and terminating, after amputation, in death from pulmonary metastases. This case will be fully reported later. 9. Jungling: Strahlentherapie 12:178, 1921. 10. Jeanbreau and Riche: Rev. de chir. 32:153, 1905. 11. Goebel: Arch. f. klin. chir. 87:191, 1908.

Journal

Archives of Surgery – American Medical Association

Published: May 1, 1922

References

  • Neoplastic Diseases
    Ewing , James