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A Rare Cause of the Chiasmal Syndrome

A Rare Cause of the Chiasmal Syndrome Abstract A 44-year-old woman presented with a chiasmal syndrome which on neurosurgical exploration was found to be due to a granular cell myoblastoma of the neurohypophysis. The presenting clinical symptoms in this and previously reported cases do not differentiate this tumor from other causes of chiasmal syndrome. The histologic appearance of these tumors is characteristic and resembles asymptomatic tumor nodules found in 6.5% of autopsies. References 1. Fust JA, Custer RP: On the neurogenesis of so-called granular cell myoblastoma . Amer J Clin Path 19:522-535, 1949. 2. Murphy GH, Dockerty MB, Broders AC: Myoblastoma . Amer J Path 25:1157-1181, 1949. 3. Abrikossoff A: Über Myome, ausgehend von der quergestreiften willkürlichen Muskulatur . Virchow Arch (Path Anat) 260:215-233, 1926.Crossref 4. Diss A: Un nouveau type de tumeur musculaire: Le rhabdomyome granulo-cellulaire . Bull Assoc Fr Etud Cancer 16:863-866, 1927. 5. Feyrter F, Lassmann G: Über das granuläre Neurom (das sogenannte Myoblastenmyom) . Wien Klin Wschr 76:760-761, 1964. 6. von Bahr G: A case of myoblastic myoma of the lacrimal sac . Acta Ophthal 16:109-115, 1938.Crossref 7. Cristini G: "Mioblastoma della palpebra" (studio anatomoclinico) . Rass Ital Ottal 15:207-223, 1946. 8. Dunnington JH: Granular cell myoblastoma of the orbit . Arch Ophthal 40:14-22, 1948.Crossref 9. Cunha SL, Lobo FG: Granular-cell myoblastoma of the anterior uvea . Brit J Ophthal 50:99-101, 1966.Crossref 10. Boyce R, Beadles CF: A further contribution to the study of the pathology of the hypophysis cerebri . J Path Bact 1:359-383, 1893.Crossref 11. Luse SA, Kernohan JW: Granular-cell tumors of the stalk and posterior lobe of the pituitary gland . Cancer 8:616-622, 1955. 12. Lüthy F, Klingler M: Der Tumorettentumor des Hypophysenhinterlappens . Schweiz Z Allg Path Bakt 14:721-729, 1951. 13. Harland WA: Granular-cell myoblastoma of the hypophyseal stalk . Cancer 6:1134-1138, 1953. 14. Glazer N, Hauser H, Slade H: Granular cell tumor of the neurohypophysis . Amer J Roentgen 76:324-326, 1956. 15. Liss L, Kahn EA: Pituicytoma, tumor of the sella turcica: A clinicopathological study . J Neurosurg 15:481-488, 1958. 16. Lima A, Antunes L, Tomé F: Pituicytoma or granular-cell myoblastoma of pituitary gland? Report of a case . J Neurosurg 17:778-782, 1960. 17. Burston J, John R, Spencer H: "Myoblastoma" of the neurohypophysis . J Path Bact 83:455-461, 1962. 18. Doron Y, Behar A, Beller AJ: Granular-cell "myoblastoma" of the neurohypophysis . J Neurosurg 22:95-99, 1965. 19. Talerman A, Dawnson-Butterworth K: Granular-cell myoblastoma of the pituitary . Postgrad Med J 42:216-218, 1966. 20. Poppen JL, Packard A: Granular cell myoblastoma of the pituitary body simulating a chromophobe adenoma . Lahey Clin Found Bull 15:25-27, 1966. 21. Moscovic EA, Azar HA: Multiple granular cell tumors ("myoblastomas"): Case report with electron microscopic observations and review of literature . Cancer 20:2032-2047, 1967.Crossref 22. Garancis JC, Komorowski RA, Kuzma JF: Granular cell myoblastoma . Cancer 25:542-550, 1970.Crossref 23. Symon L, Ganz JC, Burston J: Granular cell myoblastoma of the neurohypophysis: Report of two cases . J Neurosurg 35:82-89, 1971.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1972 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1972.01000030271010
Publisher site
See Article on Publisher Site

Abstract

Abstract A 44-year-old woman presented with a chiasmal syndrome which on neurosurgical exploration was found to be due to a granular cell myoblastoma of the neurohypophysis. The presenting clinical symptoms in this and previously reported cases do not differentiate this tumor from other causes of chiasmal syndrome. The histologic appearance of these tumors is characteristic and resembles asymptomatic tumor nodules found in 6.5% of autopsies. References 1. Fust JA, Custer RP: On the neurogenesis of so-called granular cell myoblastoma . Amer J Clin Path 19:522-535, 1949. 2. Murphy GH, Dockerty MB, Broders AC: Myoblastoma . Amer J Path 25:1157-1181, 1949. 3. Abrikossoff A: Über Myome, ausgehend von der quergestreiften willkürlichen Muskulatur . Virchow Arch (Path Anat) 260:215-233, 1926.Crossref 4. Diss A: Un nouveau type de tumeur musculaire: Le rhabdomyome granulo-cellulaire . Bull Assoc Fr Etud Cancer 16:863-866, 1927. 5. Feyrter F, Lassmann G: Über das granuläre Neurom (das sogenannte Myoblastenmyom) . Wien Klin Wschr 76:760-761, 1964. 6. von Bahr G: A case of myoblastic myoma of the lacrimal sac . Acta Ophthal 16:109-115, 1938.Crossref 7. Cristini G: "Mioblastoma della palpebra" (studio anatomoclinico) . Rass Ital Ottal 15:207-223, 1946. 8. Dunnington JH: Granular cell myoblastoma of the orbit . Arch Ophthal 40:14-22, 1948.Crossref 9. Cunha SL, Lobo FG: Granular-cell myoblastoma of the anterior uvea . Brit J Ophthal 50:99-101, 1966.Crossref 10. Boyce R, Beadles CF: A further contribution to the study of the pathology of the hypophysis cerebri . J Path Bact 1:359-383, 1893.Crossref 11. Luse SA, Kernohan JW: Granular-cell tumors of the stalk and posterior lobe of the pituitary gland . Cancer 8:616-622, 1955. 12. Lüthy F, Klingler M: Der Tumorettentumor des Hypophysenhinterlappens . Schweiz Z Allg Path Bakt 14:721-729, 1951. 13. Harland WA: Granular-cell myoblastoma of the hypophyseal stalk . Cancer 6:1134-1138, 1953. 14. Glazer N, Hauser H, Slade H: Granular cell tumor of the neurohypophysis . Amer J Roentgen 76:324-326, 1956. 15. Liss L, Kahn EA: Pituicytoma, tumor of the sella turcica: A clinicopathological study . J Neurosurg 15:481-488, 1958. 16. Lima A, Antunes L, Tomé F: Pituicytoma or granular-cell myoblastoma of pituitary gland? Report of a case . J Neurosurg 17:778-782, 1960. 17. Burston J, John R, Spencer H: "Myoblastoma" of the neurohypophysis . J Path Bact 83:455-461, 1962. 18. Doron Y, Behar A, Beller AJ: Granular-cell "myoblastoma" of the neurohypophysis . J Neurosurg 22:95-99, 1965. 19. Talerman A, Dawnson-Butterworth K: Granular-cell myoblastoma of the pituitary . Postgrad Med J 42:216-218, 1966. 20. Poppen JL, Packard A: Granular cell myoblastoma of the pituitary body simulating a chromophobe adenoma . Lahey Clin Found Bull 15:25-27, 1966. 21. Moscovic EA, Azar HA: Multiple granular cell tumors ("myoblastomas"): Case report with electron microscopic observations and review of literature . Cancer 20:2032-2047, 1967.Crossref 22. Garancis JC, Komorowski RA, Kuzma JF: Granular cell myoblastoma . Cancer 25:542-550, 1970.Crossref 23. Symon L, Ganz JC, Burston J: Granular cell myoblastoma of the neurohypophysis: Report of two cases . J Neurosurg 35:82-89, 1971.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Sep 1, 1972

References