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- Publisher
- American Medical Association
- Copyright
- Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
- ISSN
- 2168-6106
- eISSN
- 2168-6114
- DOI
- 10.1001/archinternmed.2009.266
- pmid
- 19786682
- Publisher site
- See Article on Publisher Site
Abstract
ORIGINAL INVESTIGATION A Randomized Study on the Effect of Weight Loss on Obstructive Sleep Apnea Among Obese Patients With Type 2 Diabetes The Sleep AHEAD Study Gary D. Foster, PhD; Kelley E. Borradaile, PhD; Mark H. Sanders, MD; Richard Millman, MD; Gary Zammit, PhD; Anne B. Newman, MD; Thomas A. Wadden, PhD; David Kelley, MD; Rena R. Wing, PhD; F. Xavier Pi-Sunyer, MD; David Reboussin, PhD; Samuel T. Kuna, MD; for the Sleep AHEAD Research Group of the Look AHEAD Research Group Background: The belief that weight loss improves ob- sociated with an adjusted (SE) decrease in AHI of 9.7 (2.0) structive sleep apnea (OSA) has limited empirical sup- events per hour (P .001). At 1 year, more than 3 times port. The purpose of this 4-center study was to assess the as many participants in the ILI group than in the DSE effects of weight loss on OSA over a 1-year period. group had total remission of their OSA, and the preva- lence of severe OSA among ILI participants was half that Methods: The study included 264 participants with type of the DSE group. Initial AHI and weight loss were the 2 diabetes and a mean (SD) age
Journal
JAMA Internal Medicine – American Medical Association
Published: Sep 28, 2009