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A PATTERN OF PRURITUS DUE TO CHLOROQUINE

A PATTERN OF PRURITUS DUE TO CHLOROQUINE This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor: After reading the comprehensive review of chloroquine reactions by Rees and Maibach in the September, 1963, issue of Archives of Dermatology, we wish to call your attention to a distinct and distressing skin reaction due to chloroquine, which does not appear to have received adequate emphasis in their detailed list of 105 references from the world literature. This reaction appears to be specific to the skin and is unaccompanied by any obvious systemic manifestation.It is an entirely subjective reaction characterized by a widespread pricking sensation affecting mainly the hands, feet, and scalp. We observed this reaction in male and female adult patients, predominantly Negro, who were on the accepted therapeutic doses of chloroquine for clinical malaria for immune or partially immune adults: single-dose treatment with four 200 mg tablets of chloroquine sulfate, each tablet equivalent to 150 mg of base, or with 250 mg tablets of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

A PATTERN OF PRURITUS DUE TO CHLOROQUINE

Archives of Dermatology , Volume 89 (4) – Apr 1, 1964

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Publisher
American Medical Association
Copyright
Copyright © 1964 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1964.01590280131024
Publisher site
See Article on Publisher Site

Abstract

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor: After reading the comprehensive review of chloroquine reactions by Rees and Maibach in the September, 1963, issue of Archives of Dermatology, we wish to call your attention to a distinct and distressing skin reaction due to chloroquine, which does not appear to have received adequate emphasis in their detailed list of 105 references from the world literature. This reaction appears to be specific to the skin and is unaccompanied by any obvious systemic manifestation.It is an entirely subjective reaction characterized by a widespread pricking sensation affecting mainly the hands, feet, and scalp. We observed this reaction in male and female adult patients, predominantly Negro, who were on the accepted therapeutic doses of chloroquine for clinical malaria for immune or partially immune adults: single-dose treatment with four 200 mg tablets of chloroquine sulfate, each tablet equivalent to 150 mg of base, or with 250 mg tablets of

Journal

Archives of DermatologyAmerican Medical Association

Published: Apr 1, 1964

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