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Abstract REPORT OF A CASE A 2-month-old boy had been born with a solitary nodule on his right occipitotemporal region. He was the full-term product of a 23-year-old gravida 2, para 2 woman; the pregnancy had been complicated by mild hypertension during the last eight weeks.Physical examination revealed a healthy boy with a 1.8 × 1.7-cm firm, erythematous, rubbery, slightly umbilicated nodule on the right occipitotemporal region, not attached to the underlying structures (Fig 1). A CT scan showed a normal skull and a chest roentgenogram was normal. No other abnormalities were noted. The lesion was surgically excised. Representative histologic sections are shown in Figs 2 through 4.What is your diagnosis? DIAGNOSIS: Infantile myofibromatosis (solitary type). HISTOPATHOLOGIC FINDINGS In the dermis, the tumor was composed of bundles of spindle-shaped cells with oval or elongated nucleiand eosinophilic cytoplasm having some reminis References 1. Chung EB, Enzinger FM: Congenital fibromatosis . Lab Invest 1979;40:246. 2. Chung EB, Enzinger FM: Infantile myofibromatosis . Cancer 1981;48:1807-1818.Crossref 3. Walts AE, Asch M, Raj CH: Solitary lesions of congenital fibromatosis: A rare cause of neonatal intestinal obstruction . Am J Surg Pathol 1982;6:255-260.Crossref 4. Stout AP: Juvenile fibromatosis . Cancer 1954;7:953-978.Crossref 5. Enzinger FM, Weiss SW: Soft Tissue Tumors . St Louis, CV Mosby Co, 1983, p 78. 6. Benjamin SP, Mercer RD, Hawk WA: Myofibroblastic contraction in spontaneous regression of multiple congenital mesenchymal hamartomas . Cancer 1977;40:2343-2352.Crossref 7. Jennings TA, Duray PH, Collins FS, et al: Infantile myofibromatosis: Evidence for an autosomal-dominant disorder . Am J Surg Pathol 1984;8:529-538.Crossref
Archives of Dermatology – American Medical Association
Published: Oct 1, 1987
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