Abstract Experience with N-trichloromethylmercapto-4-cychlohexane-1,2-dicarboximide has proved it to be an effective and safe remedy for seborrheic dermatitis.1 Keeping the chemical in permanent solution has been a technical problem which may have decreased its effectiveness. For the first time, the chemical in stable solution has been incorporated in a detergent shampoo* which contained also, sodium tetrathionate, a source of sulfur, and p-chloro-xylenol,2,3 an antibacterial agent. Each of these chemicals has been used and tested ex Subjects Moderate Good Excellent Response Total tensively and demonstrated to be nontoxic, as well as low in sensitizing potential. A total of 210 patients from private practice (135 females and 75 males), ranging in age from 8 months to 73 years, used the shampoo for a period of eight weeks each. Every person was examined on at least three or four occasions during this period and again two weeks or more after use References 1. The shampoo, Clear Liquid Enden, was supplied by Helene Curtis Industries, Inc. 2. Ball, F. I.: A New Treatment for Seborrheic Dermatitis , A. M. A. Arch. Dermat. & Syph. 71:696-698, 1951. 3. Zondek, B., and Finkelstein, M.: Blood Concentration of p-Chloro-Xylenol in Man Following Percutaneous, Parenteral and Rectal Application , Proc. Soc. Exper. Biol. & Med. 61:200-203, 1946. 4. Colebrook, L.: The Disinfection of the Skin , Bull. War Med. 2:73-79, 1941.
A.M.A. Archives of Dermatology – American Medical Association
Published: Aug 1, 1959
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