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A Comparison of Palpable and Nonpalpable Breast Cancers

A Comparison of Palpable and Nonpalpable Breast Cancers Abstract • Chi-square statistics were used to compare prognostic factors of 60 patients with nonpalpable breast cancer (NPBC) and 112 patients with palpable breast cancer. Noninvasive cancers were more frequent, tumor size was smaller, and nodal metastasis was significantly less frequent in the NPBC group. However, the frequency of nodal metastasis was similar when adjusted for size and grade. There was no significant difference in the incidence of age and menopausal status of the patients, histologic types, hormone receptor status, and histologic/nuclear grade between these two groups. The findings were consistent with the hypothesis that NPBCs are potentially lethal tumors and that mammograms detect them earlier, ie, these tumors are smaller, localized, and, therefore, more curable. (Arch Surg 1989;124:26-28) References 1. Shapiro S: Evidence on screening for breast cancer from a randomized trial . Cancer 1977;39:2772-2782.Crossref 2. Idem I: Imaging of the breast: A perspective . Surg Clin North Am 1984;64:1061-1072. 3. Seidman H, Gelb S, Silverberg E, et al: Survival experience in the breast cancer detection demonstration project . CA 1987;37:258-290. 4. Shapiro S, Venet W, Strax P, et al: Selection, follow-up, and analysis in the health insurance plan study: A randomized trial with breast cancer screening . NCI Monogr 1985;67:65-74. 5. Fisher E: Histologic grading of breast cancer . Pathol Annu 1980;15:239-251. 6. Fisher ER, Gresous RM, Fisher B: Pathology of invasive breast cancer: A syllabus derived from findings of the National Surgical Breast Adjuvant Project . Cancer 1975;36:1-85.Crossref 7. Strax P: Mass screening for control of breast cancer . Cancer 1984;53:665-670.Crossref 8. Bigelow R, Smith R, Goodman P, et al: Needle localization of nonpalpable breast masses . Arch Surg 1985;120:565-569.Crossref 9. Rodes N, Lopez M, Pearson D, et al: The impact of breast cancer screening of survival . Cancer 1986;57:581-585.Crossref 10. Symmonds R, Roberts J: Management of non-palpable breast abnormalities . Ann Surg 1987;205:520-528.Crossref 11. Meyer J, Kopans D, Stumper P, et al: Occult breast abnormalities: Percutaneous preoperative needle localization . Radiology 1984;150:335-337.Crossref 12. Moskowitz M: Mammographic screening: Significance of minimal breast cancers . AJR 1981;136:735-738.Crossref 13. Moskowitz M: Minimal breast cancer redux . Radiol Clin North Am 1983;21:93-113. 14. Brinton L, Hoover R, Fraumeni J: Epidemiology of minimal breast cancer . JAMA 1983;249:483-487.Crossref 15. Gullino P: Natural history of breast cancer . Cancer 1977;39:2697-2703.Crossref 16. Fisher B, Slack N, Bross I: Cancer of the breast: Size of neoplasia and prognosis . Cancer 1969;24:1071-1080.Crossref 17. Feig S, Schwartz G: Prognostic pathologic factors among breast cancers detected by screening mammography . Recent Results Cancer Res 1984;90:148-160. 18. Contesso G, Mourisse H, Friedman S, et al: Importance of histologic grade in a long-term prognosis of breast cancer: Study of 1010 patients uniformly treated at the Institut Gustave-Roussy . J Clin Oncol 1987;5:1378-1386. 19. Fisher E, Fisher B: The relationship of pathologic and some clinical discriminants to the spread of breast cancer . Int J Radiat Oncol Biol Phys 1977;2:747-750.Crossref 20. Hans-Olov A, Kilander D: Prediction of survival in breast cancer . Acta Chir Scand , 1984, (suppl 519) , pp 25-34. 21. Bishop H, Elston C, Blarney R, et al: Relationship with estrogen receptor to survival and breast cancer . Lancet 1979;2:283-284.Crossref 22. Knight W, Livingston R, Gregory E, et al: Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer . Cancer Res 1977;37:4669-4671. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

A Comparison of Palpable and Nonpalpable Breast Cancers

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Publisher
American Medical Association
Copyright
Copyright © 1989 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1989.01410010032006
Publisher site
See Article on Publisher Site

Abstract

Abstract • Chi-square statistics were used to compare prognostic factors of 60 patients with nonpalpable breast cancer (NPBC) and 112 patients with palpable breast cancer. Noninvasive cancers were more frequent, tumor size was smaller, and nodal metastasis was significantly less frequent in the NPBC group. However, the frequency of nodal metastasis was similar when adjusted for size and grade. There was no significant difference in the incidence of age and menopausal status of the patients, histologic types, hormone receptor status, and histologic/nuclear grade between these two groups. The findings were consistent with the hypothesis that NPBCs are potentially lethal tumors and that mammograms detect them earlier, ie, these tumors are smaller, localized, and, therefore, more curable. (Arch Surg 1989;124:26-28) References 1. Shapiro S: Evidence on screening for breast cancer from a randomized trial . Cancer 1977;39:2772-2782.Crossref 2. Idem I: Imaging of the breast: A perspective . Surg Clin North Am 1984;64:1061-1072. 3. Seidman H, Gelb S, Silverberg E, et al: Survival experience in the breast cancer detection demonstration project . CA 1987;37:258-290. 4. Shapiro S, Venet W, Strax P, et al: Selection, follow-up, and analysis in the health insurance plan study: A randomized trial with breast cancer screening . NCI Monogr 1985;67:65-74. 5. Fisher E: Histologic grading of breast cancer . Pathol Annu 1980;15:239-251. 6. Fisher ER, Gresous RM, Fisher B: Pathology of invasive breast cancer: A syllabus derived from findings of the National Surgical Breast Adjuvant Project . Cancer 1975;36:1-85.Crossref 7. Strax P: Mass screening for control of breast cancer . Cancer 1984;53:665-670.Crossref 8. Bigelow R, Smith R, Goodman P, et al: Needle localization of nonpalpable breast masses . Arch Surg 1985;120:565-569.Crossref 9. Rodes N, Lopez M, Pearson D, et al: The impact of breast cancer screening of survival . Cancer 1986;57:581-585.Crossref 10. Symmonds R, Roberts J: Management of non-palpable breast abnormalities . Ann Surg 1987;205:520-528.Crossref 11. Meyer J, Kopans D, Stumper P, et al: Occult breast abnormalities: Percutaneous preoperative needle localization . Radiology 1984;150:335-337.Crossref 12. Moskowitz M: Mammographic screening: Significance of minimal breast cancers . AJR 1981;136:735-738.Crossref 13. Moskowitz M: Minimal breast cancer redux . Radiol Clin North Am 1983;21:93-113. 14. Brinton L, Hoover R, Fraumeni J: Epidemiology of minimal breast cancer . JAMA 1983;249:483-487.Crossref 15. Gullino P: Natural history of breast cancer . Cancer 1977;39:2697-2703.Crossref 16. Fisher B, Slack N, Bross I: Cancer of the breast: Size of neoplasia and prognosis . Cancer 1969;24:1071-1080.Crossref 17. Feig S, Schwartz G: Prognostic pathologic factors among breast cancers detected by screening mammography . Recent Results Cancer Res 1984;90:148-160. 18. Contesso G, Mourisse H, Friedman S, et al: Importance of histologic grade in a long-term prognosis of breast cancer: Study of 1010 patients uniformly treated at the Institut Gustave-Roussy . J Clin Oncol 1987;5:1378-1386. 19. Fisher E, Fisher B: The relationship of pathologic and some clinical discriminants to the spread of breast cancer . Int J Radiat Oncol Biol Phys 1977;2:747-750.Crossref 20. Hans-Olov A, Kilander D: Prediction of survival in breast cancer . Acta Chir Scand , 1984, (suppl 519) , pp 25-34. 21. Bishop H, Elston C, Blarney R, et al: Relationship with estrogen receptor to survival and breast cancer . Lancet 1979;2:283-284.Crossref 22. Knight W, Livingston R, Gregory E, et al: Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer . Cancer Res 1977;37:4669-4671.

Journal

Archives of SurgeryAmerican Medical Association

Published: Jan 1, 1989

References