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125I-Fibrinogen Uptake and Bilateral Impedance Rheography: Diagnosis of Postoperative Venous Thrombosis

125I-Fibrinogen Uptake and Bilateral Impedance Rheography: Diagnosis of Postoperative Venous... Abstract The detection of venous thrombosis by 125I-fibrinogen uptake and impedance rheography was compared in 80 randomly selected postoperative patients. The 125I-fibrinogen test was positive in ten (12.5%). Phlebography in nine of these patients showed thromboses in seven and possible thromboses in two. The impedance test was positive in three patients who also had abnormal results from the 125I-fibrinogen test. Phlebograms showed clots above the popliteal vein in these three. The 125I-fibrinogen method is better for studying the pathogenesis and prevention of thrombosis in a group of patients. The impedance method is better for studying patients with existing thombosis. References 1. Mullick SC, Wheeler HB, Songster GF: Diagnosis of deep venous thrombosis by measurement of electrical impedance . Am J Surg 119:417-422, 1970.Crossref 2. Dmochowski JR, Adams DF, Couch NP: Impedance measurement in the diagnosis of deep venous thrombosis . Arch Surg 104:170-173, 1972.Crossref 3. Gazzaniga AB, Bartlett RH, Shobe JB: Bilateral impedance rheography in deep venous thrombosis: Role of respiratory maneuvers and saphenous occlusion . Arch Surg 106:835-837, 1973.Crossref 4. Steer ML, et al: Limitations of impedance phlebography for diagnosis of venous thrombosis . Arch Surg 106:44-48, 1973.Crossref 5. Flanc C, Kakkar VV, Clarke MB: The detection of venous thrombosis of the legs using 125-I-labelled fibrinogen . Br J Surg 55:742-747, 1968.Crossref 6. Gazzaniga AB, et al: Bilateral impedance rheography in the diagnosis of deep venous thrombosis of the legs . Arch Surg 104:515-519, 1972.Crossref 7. Jeyasingh K, et al: Criteria in radioisotope detection of venous thrombosis . Br Med J 3:500-503, 1972.Crossref 8. Nicolaides AN, et al: Optimal electrical stimulus for prevention of deep vein thrombosis . Br Med J 3:756-758, 1972.Crossref 9. Effect of aspirin on postoperative venous thrombosis: Report of the steering committee of a trial sponsored by the Medical Research Council . Lancet 2:441, 1972. 10. Gallus AS, et al: Small subcutaneous doses of heparin in prevention of venous thrombosis . N Engl J Med 288:545-551, 1973.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

125I-Fibrinogen Uptake and Bilateral Impedance Rheography: Diagnosis of Postoperative Venous Thrombosis

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References (10)

Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1974.01350250056015
Publisher site
See Article on Publisher Site

Abstract

Abstract The detection of venous thrombosis by 125I-fibrinogen uptake and impedance rheography was compared in 80 randomly selected postoperative patients. The 125I-fibrinogen test was positive in ten (12.5%). Phlebography in nine of these patients showed thromboses in seven and possible thromboses in two. The impedance test was positive in three patients who also had abnormal results from the 125I-fibrinogen test. Phlebograms showed clots above the popliteal vein in these three. The 125I-fibrinogen method is better for studying the pathogenesis and prevention of thrombosis in a group of patients. The impedance method is better for studying patients with existing thombosis. References 1. Mullick SC, Wheeler HB, Songster GF: Diagnosis of deep venous thrombosis by measurement of electrical impedance . Am J Surg 119:417-422, 1970.Crossref 2. Dmochowski JR, Adams DF, Couch NP: Impedance measurement in the diagnosis of deep venous thrombosis . Arch Surg 104:170-173, 1972.Crossref 3. Gazzaniga AB, Bartlett RH, Shobe JB: Bilateral impedance rheography in deep venous thrombosis: Role of respiratory maneuvers and saphenous occlusion . Arch Surg 106:835-837, 1973.Crossref 4. Steer ML, et al: Limitations of impedance phlebography for diagnosis of venous thrombosis . Arch Surg 106:44-48, 1973.Crossref 5. Flanc C, Kakkar VV, Clarke MB: The detection of venous thrombosis of the legs using 125-I-labelled fibrinogen . Br J Surg 55:742-747, 1968.Crossref 6. Gazzaniga AB, et al: Bilateral impedance rheography in the diagnosis of deep venous thrombosis of the legs . Arch Surg 104:515-519, 1972.Crossref 7. Jeyasingh K, et al: Criteria in radioisotope detection of venous thrombosis . Br Med J 3:500-503, 1972.Crossref 8. Nicolaides AN, et al: Optimal electrical stimulus for prevention of deep vein thrombosis . Br Med J 3:756-758, 1972.Crossref 9. Effect of aspirin on postoperative venous thrombosis: Report of the steering committee of a trial sponsored by the Medical Research Council . Lancet 2:441, 1972. 10. Gallus AS, et al: Small subcutaneous doses of heparin in prevention of venous thrombosis . N Engl J Med 288:545-551, 1973.Crossref

Journal

Archives of SurgeryAmerican Medical Association

Published: Jan 1, 1974

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