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ORIGINAL RESEARCH INTERVENTIONAL Thrombus Permeability on Dynamic CTA Predicts Good Outcome after Reperfusion Therapy X Z. Chen, X F. Shi, X X. Gong, X R. Zhang, X W. Zhong, X R. Zhang, X Y. Zhou, and X M. Lou ABSTRACT BACKGROUNDANDPURPOSE: Thrombus permeability assessed on conventional CTA is associated with neurologic outcome in patients with acute ischemic stroke. We aimed to investigate whether dynamic CTA can improve the accuracy of thrombus permeability assess- ment and its predictive value for outcome. MATERIALSANDMETHODS: We reviewed consecutive patients with acute ischemic stroke who had occlusion of the M1 segment of the middle artery cerebral artery and underwent pretreatment perfusion CT. Thrombus permeability, determined by thrombus attenuation increase (TAI), was assessed on 26-phase dynamic CTA derived from perfusion CT. TAI was defined as the maximum TAI among phases; max TAI , as TAI of peak arterial phase; TAI , as TAI on phase 13. Good outcome was defined as a 3-month mRS score of 2. peak con RESULTS: One hundred four patients were enrolled in the final analysis. The median TAI , TAI , and TAI were 30.1 HU (interquartile max peak con range, 13.0–50.2 HU), 9.5 HU (interquartile range,1.6–28.7 HU), and 6.6
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Oct 1, 2018
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