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- Publisher
- American Journal of Neuroradiology
- Copyright
- © 2017 by American Journal of Neuroradiology
- ISSN
- 0195-6108
- eISSN
- 1936-959X
- DOI
- 10.3174/ajnr.A5334
- Publisher site
- See Article on Publisher Site
Abstract
ORIGINAL RESEARCH SPINE Test-Retest and Interreader Reproducibility of Semiautomated Atlas-Based Analysis of Diffusion Tensor Imaging Data in Acute Cervical Spine Trauma in Adult Patients X D.J. Peterson, X A.M. Rutman, X D.S. Hippe, X J.G. Jarvik, X F.H. Chokshi, X M.R. Reyes, X C.H. Bombardier, and X M. Mossa-Basha ABSTRACT BACKGROUND AND PURPOSE: DTI is a tool for microstructural spinal cord injury evaluation. This study evaluated the reproducibility of a semiautomated segmentation algorithm of spinal cord DTI. MATERIALS AND METHODS: Forty-two consecutive patients undergoing acute trauma cervical spine MR imaging underwent 2 axial DTI scans in addition to their clinical scan. The datasets were put through a semiautomated probabilistic segmentation algorithm that selected white matter, gray matter, and 24 individual white matter tracts. Regional and white matter tract volume, fractional anisotropy, and mean diffusivity values were calculated. Two readers performed the nonautomated steps to evaluate interreader reproducibility. The coeffi- cient of variation and intraclass correlation coefficient were used to assess test-retest and interreader reproducibility. RESULTS: Of 42 patients, 30 had useable data. Test-retest reproducibility of fractional anisotropy was high for white matter as a whole (coefficient of variation, 3.8%; intraclass correlation coefficient, 0.93). Test-retest coefficient-of-variation ranged from 8.0%–18.2% and
Journal
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Oct 1, 2017