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Spinal cord lesions in patients with multiple sclerosis: comparison of MR pulse sequences

Spinal cord lesions in patients with multiple sclerosis: comparison of MR pulse sequences This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Hittmair, K. Articles by Kollegger, H. Search for Related Content PubMed PubMed Citation Articles by Hittmair, K. Articles by Kollegger, H. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology, Vol 17, Issue 8 1555-1565, Copyright © 1996 by American Society of Neuroradiology ARTICLES Spinal cord lesions in patients with multiple sclerosis: comparison of MR pulse sequences K Hittmair, R Mallek, D Prayer, EG Schindler and H Kollegger Department of Neuroradiology, University of Vienna (Austria). PURPOSE: To compare T2-weighted conventional spin-echo (CSE), fast spin- echo (FSE), shorttau inversion recovery (STIR) FSE, and fluid- attenuated inversion recovery (FLAIR) FSE sequences in the assessment of cervical multiple sclerosis plaques. METHODS: Twenty patients with clinically confirmed multiple sclerosis and signs of cervical cord involvement were examined on a 1.5-T MR system. Sagittal images of T2- weighted and proton density-weighted CSE sequences, T2-weighted FSE sequences with two different sets of sequence parameters, STIR-FSE sequences, and FLAIR-FSE sequences were compared by two independent observers. In addition, contrast-to-noise measurements were obtained. RESULTS: Spinal multiple sclerosis plaques were seen best on STIR-FSE images, which yielded the highest lesion contrast. Among the T2- weighted sequences, the FSE technique provided better image quality than did the CSE technique, but lesion visibility was improved only with a repetition time/echo time of 2500/90; parameters of 3000/150 provided poor lesion contrast but the best myelographic effect and overall image quality. CSE images were degraded by prominent image noise; FLAIR-FSE images showed poor lesion contrast and strong cerebrospinal fluid pulsation artifacts. CONCLUSIONS: The STIR-FSE sequence is the best choice for assessment of spinal multiple sclerosis plaques. For T2-weighted FSE sequences, shorter echo times are advantageous for spinal cord imaging, long echo times are superior for extramedullary and extradural disease. FLAIR-FSE sequences do not contribute much to spinal imaging for multiple sclerosis detection. This article has been cited by other articles: A. H. Poonawalla, P. Hou, F. A. Nelson, J. S. Wolinsky, and P. A. Narayana Cervical Spinal Cord Lesions in Multiple Sclerosis: T1-weighted Inversion-Recovery MR Imaging with Phase-Sensitive Reconstruction Radiology, December 1, 2007; 246(1): 258 - 264. Abstract Full Text PDF T. Hirai, Y. Ando, M. Yamura, M. Kitajima, Y. Hayashida, Y. Korogi, T. Yamashita, and Y. Yamashita Transthyretin-Related Familial Amyloid Polyneuropathy: Evaluation of CSF Enhancement on Serial T1-Weighted and Fluid-Attenuated Inversion Recovery Images following Intravenous Contrast Administration AJNR Am. J. Neuroradiol., September 1, 2005; 26(8): 2043 - 2048. Abstract Full Text PDF F. Agosta, B. Benedetti, M. A. Rocca, P. Valsasina, M. Rovaris, G. Comi, and M. Filippi Quantification of cervical cord pathology in primary progressive MS using diffusion tensor MRI Neurology, February 22, 2005; 64(4): 631 - 635. Abstract Full Text PDF P. D. Purdy, C. L. White III, D. L. Baer, W. H. Frawley, R. R. Reichard, G. L. Pride Jr, C. Adams, S. Miller, C. L. Hladik, and Z. Yetkin Percutaneous Translumbar Spinal Cord Compression Injury in Dogs from an Angioplasty Balloon: MR and Histopathologic Changes with Balloon Sizes and Compression Times AJNR Am. J. Neuroradiol., September 1, 2004; 25(8): 1435 - 1442. Abstract Full Text PDF J. C.J. Bot, F. Barkhof, C. H. Polman, G.J. L. a Nijeholt, V. de Groot, E. Bergers, H. J. Ader, and J. A. Castelijns Spinal cord abnormalities in recently diagnosed MS patients: Added value of spinal MRI examination Neurology, January 27, 2004; 62(2): 226 - 233. Abstract Full Text PDF A. Demir, M. Ries, C. T. W. Moonen, J.-M. Vital, J. Dehais, P. Arne, J.-M. Caille, and V. Dousset Diffusion-weighted MR Imaging with Apparent Diffusion Coefficient and Apparent Diffusion Tensor Maps in Cervical Spondylotic Myelopathy Radiology, October 1, 2003; 229(1): 37 - 43. Abstract Full Text PDF H. Oikawa, M. Sasaki, Y. Tamakawa, S. Ehara, and K. Tohyama The Substantia Nigra in Parkinson Disease: Proton Density-Weighted Spin-Echo and Fast Short Inversion Time Inversion-Recovery MR Findings AJNR Am. J. Neuroradiol., November 1, 2002; 23(10): 1747 - 1756. Abstract Full Text PDF A J P Goddard and A Gholkar Diagnostic and therapeutic radiology of the spine: an overview Imaging, October 1, 2002; 14(5): 355 - 373. Abstract Full Text PDF M. V. Okujava, F. G. Woermann, T. Hirai, and Y. Korogi Evaluation of the Human Limbic Lobe Drs Hirai and Korogi respond: Radiology, August 1, 2001; 220(2): 555 - 556. Full Text PDF M. Filippi, M. Bozzali, M. A. Horsfield, M. A. Rocca, M. P. Sormani, G. Iannucci, B. Colombo, and G. Comi A conventional and magnetization transfer MRI study of the cervical cord in patients with MS Neurology, January 11, 2000; 54(1): 207 - 207. Abstract Full Text PDF R. M. Quencer The American Journal of Neuroradiology 1980-1999 Where We Have Been: Where We Are Going AJNR Am. J. Neuroradiol., January 1, 2000; 21(1): 1 - 8. Full Text M. Bozzali, M. A. Rocca, G. Iannucci, C. Pereira, G. Comi, and M. Filippi Magnetization-Transfer Histogram Analysis of the Cervical Cord in Patients with Multiple Sclerosis AJNR Am. J. Neuroradiol., November 1, 1999; 20(10): 1803 - 1808. Abstract Full Text M. Filippi, M. A. Rocca, L. Moiola, V. Martinelli, A. Ghezzi, R. Capra, F. Salvi, and G. Comi MRI and magnetization transfer imaging changes in the brain and cervical cord of patients with Devic's neuromyelitis optica Neurology, November 1, 1999; 53(8): 1705 - 1705. Abstract Full Text PDF D. B. Hackney MR Studies of the Spinal Cord in Patients with Multiple Sclerosis: What Should We Do? AJNR Am. J. Neuroradiol., October 1, 1999; 20(9): 1581 - 1583. Full Text M. A. Rocca, G. Mastronardo, M. A. Horsfield, C. Pereira, G. Iannucci, B. Colombo, L. Moiola, G. Comi, and M. Filippi Comparison of Three MR Sequences for the Detection of Cervical Cord Lesions in Patients with Multiple Sclerosis AJNR Am. J. Neuroradiol., October 1, 1999; 20(9): 1710 - 1716. Abstract Full Text T. Okuda, Y. Korogi, Y. Shigematsu, T. Sugahara, T. Hirai, I. Ikushima, L. Liang, and M. Takahashi Brain Lesions: When Should Fluid-attenuated Inversion-Recovery Sequences Be Used in MR Evaluation? Radiology, September 1, 1999; 212(3): 793 - 798. Abstract Full Text F. Fazekas, F. Barkhof, M. Filippi, R. I. Grossman, D. K. B. Li, W. I. McDonald, H. F. McFarland, D. W. Paty, J. H. Simon, J. S. Wolinsky, et al. The contribution of magnetic resonance imaging to the diagnosis of multiple sclerosis Neurology, August 1, 1999; 53(3): 448 - 448. Abstract Full Text PDF J. S. Ross Newer Sequences for Spinal MR Imaging: Smorgasbord or Succotash of Acronyms? AJNR Am. J. Neuroradiol., March 1, 1999; 20(3): 361 - 373. Full Text J. C. J. Bot, F. Barkhof, G. L. a Nijeholt, D. van Schaardenburg, A. E. Voskuyl, H. J. Ader, J. A. L. Pijnenburg, C. H. Polman, B. M. J. Uitdehaag, E. G. J. Vermeulen, et al. Differentiation of Multiple Sclerosis from Other Inflammatory Disorders and Cerebrovascular Disease: Value of Spinal MR Imaging Radiology, April 1, 2002; 223(1): 46 - 56. Abstract Full Text PDF Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Spinal cord lesions in patients with multiple sclerosis: comparison of MR pulse sequences

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American Journal of Neuroradiology
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Copyright © 2010 by the American Society of Neuroradiology.
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0195-6108
eISSN
1936-959X
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Abstract

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Hittmair, K. Articles by Kollegger, H. Search for Related Content PubMed PubMed Citation Articles by Hittmair, K. Articles by Kollegger, H. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology, Vol 17, Issue 8 1555-1565, Copyright © 1996 by American Society of Neuroradiology ARTICLES Spinal cord lesions in patients with multiple sclerosis: comparison of MR pulse sequences K Hittmair, R Mallek, D Prayer, EG Schindler and H Kollegger Department of Neuroradiology, University of Vienna (Austria). PURPOSE: To compare T2-weighted conventional spin-echo (CSE), fast spin- echo (FSE), shorttau inversion recovery (STIR) FSE, and fluid- attenuated inversion recovery (FLAIR) FSE sequences in the assessment of cervical multiple sclerosis plaques. METHODS: Twenty patients with clinically confirmed multiple sclerosis and signs of cervical cord involvement were examined on a 1.5-T MR system. Sagittal images of T2- weighted and proton density-weighted CSE sequences, T2-weighted FSE sequences with two different sets of sequence parameters, STIR-FSE sequences, and FLAIR-FSE sequences were compared by two independent observers. In addition, contrast-to-noise measurements were obtained. RESULTS: Spinal multiple sclerosis plaques were seen best on STIR-FSE images, which yielded the highest lesion contrast. Among the T2- weighted sequences, the FSE technique provided better image quality than did the CSE technique, but lesion visibility was improved only with a repetition time/echo time of 2500/90; parameters of 3000/150 provided poor lesion contrast but the best myelographic effect and overall image quality. CSE images were degraded by prominent image noise; FLAIR-FSE images showed poor lesion contrast and strong cerebrospinal fluid pulsation artifacts. CONCLUSIONS: The STIR-FSE sequence is the best choice for assessment of spinal multiple sclerosis plaques. For T2-weighted FSE sequences, shorter echo times are advantageous for spinal cord imaging, long echo times are superior for extramedullary and extradural disease. FLAIR-FSE sequences do not contribute much to spinal imaging for multiple sclerosis detection. This article has been cited by other articles: A. H. Poonawalla, P. Hou, F. A. Nelson, J. S. Wolinsky, and P. A. Narayana Cervical Spinal Cord Lesions in Multiple Sclerosis: T1-weighted Inversion-Recovery MR Imaging with Phase-Sensitive Reconstruction Radiology, December 1, 2007; 246(1): 258 - 264. Abstract Full Text PDF T. Hirai, Y. Ando, M. Yamura, M. Kitajima, Y. Hayashida, Y. Korogi, T. Yamashita, and Y. Yamashita Transthyretin-Related Familial Amyloid Polyneuropathy: Evaluation of CSF Enhancement on Serial T1-Weighted and Fluid-Attenuated Inversion Recovery Images following Intravenous Contrast Administration AJNR Am. J. Neuroradiol., September 1, 2005; 26(8): 2043 - 2048. Abstract Full Text PDF F. Agosta, B. Benedetti, M. A. Rocca, P. Valsasina, M. Rovaris, G. Comi, and M. Filippi Quantification of cervical cord pathology in primary progressive MS using diffusion tensor MRI Neurology, February 22, 2005; 64(4): 631 - 635. Abstract Full Text PDF P. D. Purdy, C. L. White III, D. L. Baer, W. H. Frawley, R. R. Reichard, G. L. Pride Jr, C. Adams, S. Miller, C. L. Hladik, and Z. Yetkin Percutaneous Translumbar Spinal Cord Compression Injury in Dogs from an Angioplasty Balloon: MR and Histopathologic Changes with Balloon Sizes and Compression Times AJNR Am. J. Neuroradiol., September 1, 2004; 25(8): 1435 - 1442. Abstract Full Text PDF J. C.J. Bot, F. Barkhof, C. H. Polman, G.J. L. a Nijeholt, V. de Groot, E. Bergers, H. J. Ader, and J. A. Castelijns Spinal cord abnormalities in recently diagnosed MS patients: Added value of spinal MRI examination Neurology, January 27, 2004; 62(2): 226 - 233. Abstract Full Text PDF A. Demir, M. Ries, C. T. W. Moonen, J.-M. Vital, J. Dehais, P. Arne, J.-M. Caille, and V. Dousset Diffusion-weighted MR Imaging with Apparent Diffusion Coefficient and Apparent Diffusion Tensor Maps in Cervical Spondylotic Myelopathy Radiology, October 1, 2003; 229(1): 37 - 43. Abstract Full Text PDF H. Oikawa, M. Sasaki, Y. Tamakawa, S. Ehara, and K. Tohyama The Substantia Nigra in Parkinson Disease: Proton Density-Weighted Spin-Echo and Fast Short Inversion Time Inversion-Recovery MR Findings AJNR Am. J. Neuroradiol., November 1, 2002; 23(10): 1747 - 1756. Abstract Full Text PDF A J P Goddard and A Gholkar Diagnostic and therapeutic radiology of the spine: an overview Imaging, October 1, 2002; 14(5): 355 - 373. Abstract Full Text PDF M. V. Okujava, F. G. Woermann, T. Hirai, and Y. Korogi Evaluation of the Human Limbic Lobe Drs Hirai and Korogi respond: Radiology, August 1, 2001; 220(2): 555 - 556. Full Text PDF M. Filippi, M. Bozzali, M. A. Horsfield, M. A. Rocca, M. P. Sormani, G. Iannucci, B. Colombo, and G. Comi A conventional and magnetization transfer MRI study of the cervical cord in patients with MS Neurology, January 11, 2000; 54(1): 207 - 207. Abstract Full Text PDF R. M. Quencer The American Journal of Neuroradiology 1980-1999 Where We Have Been: Where We Are Going AJNR Am. J. Neuroradiol., January 1, 2000; 21(1): 1 - 8. Full Text M. Bozzali, M. A. Rocca, G. Iannucci, C. Pereira, G. Comi, and M. Filippi Magnetization-Transfer Histogram Analysis of the Cervical Cord in Patients with Multiple Sclerosis AJNR Am. J. Neuroradiol., November 1, 1999; 20(10): 1803 - 1808. Abstract Full Text M. Filippi, M. A. Rocca, L. Moiola, V. Martinelli, A. Ghezzi, R. Capra, F. Salvi, and G. Comi MRI and magnetization transfer imaging changes in the brain and cervical cord of patients with Devic's neuromyelitis optica Neurology, November 1, 1999; 53(8): 1705 - 1705. Abstract Full Text PDF D. B. Hackney MR Studies of the Spinal Cord in Patients with Multiple Sclerosis: What Should We Do? AJNR Am. J. Neuroradiol., October 1, 1999; 20(9): 1581 - 1583. Full Text M. A. Rocca, G. Mastronardo, M. A. Horsfield, C. Pereira, G. Iannucci, B. Colombo, L. Moiola, G. Comi, and M. Filippi Comparison of Three MR Sequences for the Detection of Cervical Cord Lesions in Patients with Multiple Sclerosis AJNR Am. J. Neuroradiol., October 1, 1999; 20(9): 1710 - 1716. Abstract Full Text T. Okuda, Y. Korogi, Y. Shigematsu, T. Sugahara, T. Hirai, I. Ikushima, L. Liang, and M. Takahashi Brain Lesions: When Should Fluid-attenuated Inversion-Recovery Sequences Be Used in MR Evaluation? Radiology, September 1, 1999; 212(3): 793 - 798. Abstract Full Text F. Fazekas, F. Barkhof, M. Filippi, R. I. Grossman, D. K. B. Li, W. I. McDonald, H. F. McFarland, D. W. Paty, J. H. Simon, J. S. Wolinsky, et al. The contribution of magnetic resonance imaging to the diagnosis of multiple sclerosis Neurology, August 1, 1999; 53(3): 448 - 448. Abstract Full Text PDF J. S. Ross Newer Sequences for Spinal MR Imaging: Smorgasbord or Succotash of Acronyms? AJNR Am. J. Neuroradiol., March 1, 1999; 20(3): 361 - 373. Full Text J. C. J. Bot, F. Barkhof, G. L. a Nijeholt, D. van Schaardenburg, A. E. Voskuyl, H. J. Ader, J. A. L. Pijnenburg, C. H. Polman, B. M. J. Uitdehaag, E. G. J. Vermeulen, et al. Differentiation of Multiple Sclerosis from Other Inflammatory Disorders and Cerebrovascular Disease: Value of Spinal MR Imaging Radiology, April 1, 2002; 223(1): 46 - 56. Abstract Full Text PDF Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Sep 1, 1996

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