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Reply: Donna R. Roberts, Joe Tidwell and J. Andrew Taylor AJNR Am J Neuroradiol 2024, 45 (5) E5 doi: https://doi.org/10.3174/ajnr.A8278 http://www.ajnr.org/content/45/5/E5 This information is current as of June 3, 2024. 5 REPLY: infrared spectroscopy to measure CBF during spaceflight. We are awaiting, with interest, the results of this study. e thank Drs Bateman and Bateman for their comments. Given the complexity of factors that may contribute to altered 1 2 WIn their letter and in their review, Bateman and cerebral perfusion and spaceflight-associated neuro-ocular syn- Bateman highlight the limitations of the head-down tilt bedrest drome (SANS) development, ultimately a multimodal approach, model as an analog for cerebrovascular changes that may occur using both inflight and ground-based methods for measuring cer- during spaceflight. In this regard, we stress the importance for ebral perfusion in astronauts, will be needed to gain a better space agencies and commercial spaceflight providers to prioritize understanding of the impact of spaceflight on cerebrovascular studies of cerebral perfusion in astronauts. physiology. In addition, these studies would provide essential In addition to the limitations inherent in the head-down data for developing evidence-based protocols to reduce the risk tilt bedrest model, it is important to keep in mind the difficul- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

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References (5)

Publisher
American Journal of Neuroradiology
Copyright
© 2024 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.a8278
Publisher site
See Article on Publisher Site

Abstract

Donna R. Roberts, Joe Tidwell and J. Andrew Taylor AJNR Am J Neuroradiol 2024, 45 (5) E5 doi: https://doi.org/10.3174/ajnr.A8278 http://www.ajnr.org/content/45/5/E5 This information is current as of June 3, 2024. 5 REPLY: infrared spectroscopy to measure CBF during spaceflight. We are awaiting, with interest, the results of this study. e thank Drs Bateman and Bateman for their comments. Given the complexity of factors that may contribute to altered 1 2 WIn their letter and in their review, Bateman and cerebral perfusion and spaceflight-associated neuro-ocular syn- Bateman highlight the limitations of the head-down tilt bedrest drome (SANS) development, ultimately a multimodal approach, model as an analog for cerebrovascular changes that may occur using both inflight and ground-based methods for measuring cer- during spaceflight. In this regard, we stress the importance for ebral perfusion in astronauts, will be needed to gain a better space agencies and commercial spaceflight providers to prioritize understanding of the impact of spaceflight on cerebrovascular studies of cerebral perfusion in astronauts. physiology. In addition, these studies would provide essential In addition to the limitations inherent in the head-down data for developing evidence-based protocols to reduce the risk tilt bedrest model, it is important to keep in mind the difficul-

Journal

American Journal of NeuroradiologyAmerican Journal of Neuroradiology

Published: May 1, 2024

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