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Reply: REPLY: anti-NMDA receptor encephalitis, and they reached a consensus that all the patients had isolated anti-NMDA receptor encephalitis. e thank Drs Scheel and Finke for their insightful comments Furthermore, the virus antibody tests such as those for herpes sim- Wand for sharing their opinions on our article, “Brain MR plex virus and cytomegalovirus antibodies in the CSF were regularly Imaging Characteristics of Patients with Anti-N-Methyl-D- performed in our hospital when encephalitis was suspected, and the Aspartate Receptor Encephalitis and Their Associations with results of virus antibody tests were negative in all the patients in our 2-Year Clinical Outcome.” We agree with Drs Scheel and Finke’s group. Despite the above effort, it is still very difficult to fully exclude important comments that it is crucial to differentiate isolated HSE followed by anti-NMDA receptor encephalitis from isolated anti-N-methyl-D-aspartate (NMDA) receptor encephalitis from anti-NMDA receptor encephalitis in the routine clinical setting. herpes simplex encephalitis (HSE) followed by anti-NMDA re- Thus, our results about the type 4 lesions of patients with anti- ceptor encephalitis. NMDA receptor encephalitis should be interpreted carefully and In this publication, we tried to investigate the brain MR imag- need to be further validated. Further studies are warranted to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

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Publisher
American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A5800
Publisher site
See Article on Publisher Site

Abstract

REPLY: anti-NMDA receptor encephalitis, and they reached a consensus that all the patients had isolated anti-NMDA receptor encephalitis. e thank Drs Scheel and Finke for their insightful comments Furthermore, the virus antibody tests such as those for herpes sim- Wand for sharing their opinions on our article, “Brain MR plex virus and cytomegalovirus antibodies in the CSF were regularly Imaging Characteristics of Patients with Anti-N-Methyl-D- performed in our hospital when encephalitis was suspected, and the Aspartate Receptor Encephalitis and Their Associations with results of virus antibody tests were negative in all the patients in our 2-Year Clinical Outcome.” We agree with Drs Scheel and Finke’s group. Despite the above effort, it is still very difficult to fully exclude important comments that it is crucial to differentiate isolated HSE followed by anti-NMDA receptor encephalitis from isolated anti-N-methyl-D-aspartate (NMDA) receptor encephalitis from anti-NMDA receptor encephalitis in the routine clinical setting. herpes simplex encephalitis (HSE) followed by anti-NMDA re- Thus, our results about the type 4 lesions of patients with anti- ceptor encephalitis. NMDA receptor encephalitis should be interpreted carefully and In this publication, we tried to investigate the brain MR imag- need to be further validated. Further studies are warranted to

Journal

American Journal of NeuroradiologyAmerican Journal of Neuroradiology

Published: Nov 1, 2018

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