ORIGINAL RESEARCH HEAD & NECK Real-Time Ultrasound Image Fusion with FDG-PET/CT to Perform Fused Image-Guided Fine-Needle Aspiration in Neck Nodes: Feasibility and Diagnostic Value P.K. de Koekkoek-Doll, M. Maas, W. Vogel, J. Castelijns, L. Smit, I. Zavrakidis, R. Beets-Tan, and M. van den Brekel ABSTRACT BACKGROUND AND PURPOSE: New imaging techniques such as hybrid imaging of ultrasound and FDG-PET/CT are available but not yet investigated for node staging. The aim of the study was to evaluate the feasibility and added diagnostic value of real-time image-fused ultrasound-guided ﬁne-needle aspiration with FDG-PET/CT data for node staging. MATERIALS AND METHODS: Ninety-six patients who were referred for cervical lymph node staging with FDG-PET/CT before ultra- sound were prospectively included. After routine ultrasound-guided ﬁne-needle aspiration, all FDG-PET-positive nodes were marked on FDG-PET/CT, and real-time image fusing of ultrasound and FDG-PET/CT was performed using the electromagnetic navigation system PercuNav. Already-punctured nodes were conﬁrmed to be PET-positive, and additional fused-ultrasound-guided ﬁne-needle aspiration was performed in previously missed PET-positive nodes. RESULTS: Of 96 patients, 87 (91%) patients had suspicious nodes requiring ﬁne-needle aspiration cytology. Ultrasound-guided ﬁne- needle aspiration was performed in 175 nodes. Cytology was inconclusive in 9/175 (5%) nodes, and 85/166 (51%) nodes were malig- nant.
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Mar 1, 2021