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Prognostic Accuracy of Fetal MRI in Predicting Postnatal Neurodevelopmental Outcome

Prognostic Accuracy of Fetal MRI in Predicting Postnatal Neurodevelopmental Outcome ORIGINAL RESEARCH PEDIATRICS Prognostic Accuracy of Fetal MRI in Predicting Postnatal Neurodevelopmental Outcome M. Wilson, K. Muir, D. Reddy, R. Webster, C. Kapoor, and E. Miller ABSTRACT BACKGROUND AND PURPOSE: The superior diagnostic accuracy of fetal MR imaging in detecting fetal brain abnormalities has been previously demonstrated; however, the ability of fetal MR imaging to prognosticate postnatal outcome is not well-studied. We performed a retrospective analysis to determine the prognostic accuracy of fetal MR imaging in predicting postnatal neurode- velopmental outcome. MATERIALS AND METHODS: We identified all fetal MR imaging performed at the Children's Hospital of Eastern Ontario during a 10-year period and assessed agreement between prenatal prognosis and postnatal outcome. Prenatal prognosis was determined by a pediatric neurologist who reviewed the fetal MR imaging report and categorized each pregnancy as having a favorable, indetermi- nate, or poor prognosis. Assessment of postnatal neurodevelopmental outcome was made solely on the basis of the child’s Gross Motor Function Classification System score and whether the child developed epilepsy. Postnatal outcome was categorized as favorable, intermediate, or poor. We also assessed the diagnostic accuracy of fetal MR imaging by comparing prenatal and post- natal imaging diagnoses. RESULTS: We reviewed 145 fetal MR images: http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Prognostic Accuracy of Fetal MRI in Predicting Postnatal Neurodevelopmental Outcome

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Publisher
American Journal of Neuroradiology
Copyright
© 2020 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A6770
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL RESEARCH PEDIATRICS Prognostic Accuracy of Fetal MRI in Predicting Postnatal Neurodevelopmental Outcome M. Wilson, K. Muir, D. Reddy, R. Webster, C. Kapoor, and E. Miller ABSTRACT BACKGROUND AND PURPOSE: The superior diagnostic accuracy of fetal MR imaging in detecting fetal brain abnormalities has been previously demonstrated; however, the ability of fetal MR imaging to prognosticate postnatal outcome is not well-studied. We performed a retrospective analysis to determine the prognostic accuracy of fetal MR imaging in predicting postnatal neurode- velopmental outcome. MATERIALS AND METHODS: We identified all fetal MR imaging performed at the Children's Hospital of Eastern Ontario during a 10-year period and assessed agreement between prenatal prognosis and postnatal outcome. Prenatal prognosis was determined by a pediatric neurologist who reviewed the fetal MR imaging report and categorized each pregnancy as having a favorable, indetermi- nate, or poor prognosis. Assessment of postnatal neurodevelopmental outcome was made solely on the basis of the child’s Gross Motor Function Classification System score and whether the child developed epilepsy. Postnatal outcome was categorized as favorable, intermediate, or poor. We also assessed the diagnostic accuracy of fetal MR imaging by comparing prenatal and post- natal imaging diagnoses. RESULTS: We reviewed 145 fetal MR images:

Journal

American Journal of NeuroradiologyAmerican Journal of Neuroradiology

Published: Nov 1, 2020

References