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MR Imaging Findings in 2 Cases of Late Infantile GM1 Gangliosidosis

MR Imaging Findings in 2 Cases of Late Infantile GM1 Gangliosidosis This Article Figures Only Full Text Full Text (PDF) All Versions of this Article: ajnr.A1508v1 30/7/1325 most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by De Grandis, E. Articles by Rossi, A. Search for Related Content PubMed PubMed Citation Articles by De Grandis, E. Articles by Rossi, A. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 30:1325-1327, August 2009 © 2009 American Society of Neuroradiology Case Report PEDIATRICS MR Imaging Findings in 2 Cases of Late Infantile GM1 Gangliosidosis E. De Grandis a , M. Di Rocco b , A. Pessagno a , E. Veneselli a and A. Rossi c a Division of Child Neuropsychiatry, Gaslini Institute, University of Genoa, Genoa, Italy b Second Unit of Pediatrics, Gaslini Institute, Genoa, Italy c Department of Pediatric Neuroradiology, Gaslini Institute, Genoa, Italy Please address correspondence to Elisa De Grandis, MD, Division of Child Neuropsychiatry, G Gaslini Institute, University of Genoa, Largo Gaslini 5, 16148 Genova Quarto, Italy; e-mail: elisadegrandis@yahoo.it SUMMARY: Late infantile GM1 gangliosidosis is a rare lysosomal disorder characterized by mental deterioration and progressive spastic, cerebellar, and extrapyramidal signs, without facial dysmorphisms and organomegaly. Neuroimaging findings have been reported in only a few cases. Here we report on predominant globus pallidus MR signal-intensity abnormalities in 2 patients with the late infantile form of GM1 gangliosidosis. Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

MR Imaging Findings in 2 Cases of Late Infantile GM1 Gangliosidosis

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Publisher
American Journal of Neuroradiology
Copyright
Copyright © 2010 by the American Society of Neuroradiology.
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A1508
Publisher site
See Article on Publisher Site

Abstract

This Article Figures Only Full Text Full Text (PDF) All Versions of this Article: ajnr.A1508v1 30/7/1325 most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by De Grandis, E. Articles by Rossi, A. Search for Related Content PubMed PubMed Citation Articles by De Grandis, E. Articles by Rossi, A. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 30:1325-1327, August 2009 © 2009 American Society of Neuroradiology Case Report PEDIATRICS MR Imaging Findings in 2 Cases of Late Infantile GM1 Gangliosidosis E. De Grandis a , M. Di Rocco b , A. Pessagno a , E. Veneselli a and A. Rossi c a Division of Child Neuropsychiatry, Gaslini Institute, University of Genoa, Genoa, Italy b Second Unit of Pediatrics, Gaslini Institute, Genoa, Italy c Department of Pediatric Neuroradiology, Gaslini Institute, Genoa, Italy Please address correspondence to Elisa De Grandis, MD, Division of Child Neuropsychiatry, G Gaslini Institute, University of Genoa, Largo Gaslini 5, 16148 Genova Quarto, Italy; e-mail: elisadegrandis@yahoo.it SUMMARY: Late infantile GM1 gangliosidosis is a rare lysosomal disorder characterized by mental deterioration and progressive spastic, cerebellar, and extrapyramidal signs, without facial dysmorphisms and organomegaly. Neuroimaging findings have been reported in only a few cases. Here we report on predominant globus pallidus MR signal-intensity abnormalities in 2 patients with the late infantile form of GM1 gangliosidosis. Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X

Journal

American Journal of NeuroradiologyAmerican Journal of Neuroradiology

Published: Aug 1, 2009

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