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Investigation of a New Version of the Liquid Embolic Agent PHIL with Extra-Low-Viscosity in an Endovascular Embolization Model

Investigation of a New Version of the Liquid Embolic Agent PHIL with Extra-Low-Viscosity in an... ORIGINAL RESEARCH INTERVENTIONAL Investigation of a New Version of the Liquid Embolic Agent PHIL with Extra-Low-Viscosity in an Endovascular Embolization Model X D.F. Vollherbst, X R. Otto, X M. Hantz, X C. Ulfert, X H.U. Kauczor, X M. Bendszus, X C.M. Sommer, and X M.A. Mo¨hlenbruch ABSTRACT BACKGROUND AND PURPOSE: The type and composition of an embolic agent have a relevant influence on the performance of endovascular embolization. The aim of this study was to investigate a new version of the liquid embolic agent precipitating hydrophobic injectable liquid (PHIL) with extra-low-viscosity in an in vivo embolization model. MATERIALS AND METHODS: Twenty-four embolization procedures were performed in the porcine rete mirabile. Eight embolizations were performed with PHIL 25% low viscosity, Squid 12, and standard PHIL 25%, respectively. Procedure time, required volume of embolic agent,visibilityoftheembolicagent,embolizationcontrol,embolizationextent(ie,penetrationoftheretemirabile),amountofreflux,and degree of embolization distal to the rete mirabile were assessed. RESULTS: All embolic agents were adequately visible. The embolization extent was not significantly different among the 3 investigated agents; however, there was a tendency toward a higher embolization extent for PHIL 25% low viscosity (median embolization extent: 88% [PHIL 25% low viscosity]; 65% [Squid 12]; 60% [PHIL 25%]; P .146). The amount of reflux was significantly http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Investigation of a New Version of the Liquid Embolic Agent PHIL with Extra-Low-Viscosity in an Endovascular Embolization Model

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Publisher
American Journal of Neuroradiology
Copyright
© 2018 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A5750
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL RESEARCH INTERVENTIONAL Investigation of a New Version of the Liquid Embolic Agent PHIL with Extra-Low-Viscosity in an Endovascular Embolization Model X D.F. Vollherbst, X R. Otto, X M. Hantz, X C. Ulfert, X H.U. Kauczor, X M. Bendszus, X C.M. Sommer, and X M.A. Mo¨hlenbruch ABSTRACT BACKGROUND AND PURPOSE: The type and composition of an embolic agent have a relevant influence on the performance of endovascular embolization. The aim of this study was to investigate a new version of the liquid embolic agent precipitating hydrophobic injectable liquid (PHIL) with extra-low-viscosity in an in vivo embolization model. MATERIALS AND METHODS: Twenty-four embolization procedures were performed in the porcine rete mirabile. Eight embolizations were performed with PHIL 25% low viscosity, Squid 12, and standard PHIL 25%, respectively. Procedure time, required volume of embolic agent,visibilityoftheembolicagent,embolizationcontrol,embolizationextent(ie,penetrationoftheretemirabile),amountofreflux,and degree of embolization distal to the rete mirabile were assessed. RESULTS: All embolic agents were adequately visible. The embolization extent was not significantly different among the 3 investigated agents; however, there was a tendency toward a higher embolization extent for PHIL 25% low viscosity (median embolization extent: 88% [PHIL 25% low viscosity]; 65% [Squid 12]; 60% [PHIL 25%]; P .146). The amount of reflux was significantly

Journal

American Journal of NeuroradiologyAmerican Journal of Neuroradiology

Published: Sep 1, 2018

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