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ORIGINAL RESEARCH INTERVENTIONAL Fast Stent Retrieval Improves Recanalization Rates of Thrombectomy: Experimental Study on Different Thrombi S. Soize, L. Pierot, M. Mirza, G. Gunning, M. Gilvarry, M. Gawlitza, D. Vivien, M. Zuber, and E. Touzé ABSTRACT BACKGROUND AND PURPOSE: About 20% of patients with acute ischemic stroke due to large-artery occlusion do not achieve re- canalization with mechanical thrombectomy. We aimed to determine whether the speed of retrieval of the stent retriever influen- ces the efficacy in removing different clot types. MATERIALS AND METHODS: Sixty mechanical thrombectomies were performed using an in vitro pulsatile cerebrovascular circula- tion model with controlled pressure and flow rate. Experiments were dichotomized into fast and slow retrieval using a wedging technique, in which the stent retriever and distal catheter are retrieved together. We used 3 different clot types: erythrocyte-rich, fibrin-rich, and friable clots. Primary end points were complete (TICI 3) and successful (TICI 2b–3) recanalizations. Secondary meas- ures were distal and new territory embolizations. RESULTS: Fast retrieval was more frequently associated with complete (RR¼ 1.83; 95% CI, 1.12–2.99) and successful recanalization (RR¼ 1.50; 95% CI, 1.03–2.19) than slow retrieval, without a difference in distal embolization (RR¼ 0.75; 95% CI, 0.29–1.90). There were no emboli
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Jun 1, 2020
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