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Diffusion Tensor Imaging in Chronic Subdural Hematoma: Correlation between Clinical Signs and Fractional Anisotropy in the Pyramidal Tract

Diffusion Tensor Imaging in Chronic Subdural Hematoma: Correlation between Clinical Signs and... This Article Figures Only Full Text Full Text (PDF) All Versions of this Article: ajnr.A1001v1 29/6/1159 most recent Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Yokoyama, K. Articles by Kuroiwa, T. Search for Related Content PubMed PubMed Citation Articles by Yokoyama, K. Articles by Kuroiwa, T. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 29:1159-1163, June-July 2008 © 2008 American Society of Neuroradiology BRAIN Diffusion Tensor Imaging in Chronic Subdural Hematoma: Correlation between Clinical Signs and Fractional Anisotropy in the Pyramidal Tract K. Yokoyama a , M. Matsuki a ,b , H. Shimano a , S. Sumioka a , T. Ikenaga a , K. Hanabusa a , S. Yasuda a , H. Inoue a , T. Watanabe a , M. Miyashita a ,b , R. Hiramatsu a , K. Murao a , A. Kondo a , H. Tanabe a and T. Kuroiwa c a Department of Neurosurgery, Brain and Spine Surgery Center and Research Institution of Microvascular Decompression, Shiroyama Hospital, Osaka, Japan b Department of Radiology, Brain and Spine Surgery Center and Research Institution of Microvascular Decompression, Shiroyama Hospital, Osaka, Japan c Department of Neurosurgery, Osaka Medical College, Takatsuki, Osaka, Japan Please address correspondence to Kunio Yokoyama, MD, Department of Neurosurgery, Brain and Spine Surgery Center and Research Institution of Microvascular Decompression, Shiroyama Hospital, Osaka, Japan, 2-8-1 Habikino, Habikino City, Osaka, 583-0872, Japan; e-mail: neu100@poh.osaka-med.ac.jp BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) was introduced as a good technique to evaluate structural abnormalities in the white matter. In this study, we used DTI to examine anisotropic changes of the pyramidal tracts displaced by chronic subdural hematoma (CSDH). MATERIALS AND METHODS: Twenty-six patients with unilateral CSDH underwent DTI before and after surgery. We measured fractional anisotropy (FA) values in pyramidal tracts of bilateral cerebral peduncles and calculated the ratio of the FA value on the lesion side to that on the contralateral side (FA ratio) and compared the ratios with motor weakness. Moreover, the relationships between FA ratios and clinical factors such as age, sex, midline shift, interval from trauma, and hematoma attenuation on CT were evaluated. RESULTS: FA values of pyramidal tracts on the lesion side were significantly lower than those on the contralateral side (0.66 ± 0.07 versus 0.74 ± 0.05, P < .0001). The FA ratio was correlated to the severity of motor weakness ( r 2 = 0.32, P = .002). FA ratios after surgery improved significantly compared with those before surgery (0.96 ± 0.08 versus 0.89 ± 0.07, P = .0004). Intervals from trauma and the midline shift were significantly associated with decreased FA ratios ( P = .0008 and P = .037). CONCLUSIONS: In patients with CSDH, a reversible decrease of FA in the affected pyramidal tract on DTI was correlated to motor weakness. These anisotropic changes were considered to be caused by a reversible distortion of neuron fibers and vasogenic edema due to the hematoma. This article has been cited by other articles: Y. Kusano, T. Seguchi, T. Horiuchi, Y. Kakizawa, T. Kobayashi, Y. Tanaka, K. Seguchi, and K. Hongo Prediction of Functional Outcome in Acute Cerebral Hemorrhage Using Diffusion Tensor Imaging at 3T: A Prospective Study AJNR Am. J. Neuroradiol., September 1, 2009; 30(8): 1561 - 1565. Abstract Full Text PDF Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Diffusion Tensor Imaging in Chronic Subdural Hematoma: Correlation between Clinical Signs and Fractional Anisotropy in the Pyramidal Tract

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Publisher
American Journal of Neuroradiology
Copyright
Copyright © 2010 by the American Society of Neuroradiology.
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A1001
Publisher site
See Article on Publisher Site

Abstract

This Article Figures Only Full Text Full Text (PDF) All Versions of this Article: ajnr.A1001v1 29/6/1159 most recent Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Yokoyama, K. Articles by Kuroiwa, T. Search for Related Content PubMed PubMed Citation Articles by Yokoyama, K. Articles by Kuroiwa, T. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 29:1159-1163, June-July 2008 © 2008 American Society of Neuroradiology BRAIN Diffusion Tensor Imaging in Chronic Subdural Hematoma: Correlation between Clinical Signs and Fractional Anisotropy in the Pyramidal Tract K. Yokoyama a , M. Matsuki a ,b , H. Shimano a , S. Sumioka a , T. Ikenaga a , K. Hanabusa a , S. Yasuda a , H. Inoue a , T. Watanabe a , M. Miyashita a ,b , R. Hiramatsu a , K. Murao a , A. Kondo a , H. Tanabe a and T. Kuroiwa c a Department of Neurosurgery, Brain and Spine Surgery Center and Research Institution of Microvascular Decompression, Shiroyama Hospital, Osaka, Japan b Department of Radiology, Brain and Spine Surgery Center and Research Institution of Microvascular Decompression, Shiroyama Hospital, Osaka, Japan c Department of Neurosurgery, Osaka Medical College, Takatsuki, Osaka, Japan Please address correspondence to Kunio Yokoyama, MD, Department of Neurosurgery, Brain and Spine Surgery Center and Research Institution of Microvascular Decompression, Shiroyama Hospital, Osaka, Japan, 2-8-1 Habikino, Habikino City, Osaka, 583-0872, Japan; e-mail: neu100@poh.osaka-med.ac.jp BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) was introduced as a good technique to evaluate structural abnormalities in the white matter. In this study, we used DTI to examine anisotropic changes of the pyramidal tracts displaced by chronic subdural hematoma (CSDH). MATERIALS AND METHODS: Twenty-six patients with unilateral CSDH underwent DTI before and after surgery. We measured fractional anisotropy (FA) values in pyramidal tracts of bilateral cerebral peduncles and calculated the ratio of the FA value on the lesion side to that on the contralateral side (FA ratio) and compared the ratios with motor weakness. Moreover, the relationships between FA ratios and clinical factors such as age, sex, midline shift, interval from trauma, and hematoma attenuation on CT were evaluated. RESULTS: FA values of pyramidal tracts on the lesion side were significantly lower than those on the contralateral side (0.66 ± 0.07 versus 0.74 ± 0.05, P < .0001). The FA ratio was correlated to the severity of motor weakness ( r 2 = 0.32, P = .002). FA ratios after surgery improved significantly compared with those before surgery (0.96 ± 0.08 versus 0.89 ± 0.07, P = .0004). Intervals from trauma and the midline shift were significantly associated with decreased FA ratios ( P = .0008 and P = .037). CONCLUSIONS: In patients with CSDH, a reversible decrease of FA in the affected pyramidal tract on DTI was correlated to motor weakness. These anisotropic changes were considered to be caused by a reversible distortion of neuron fibers and vasogenic edema due to the hematoma. This article has been cited by other articles: Y. Kusano, T. Seguchi, T. Horiuchi, Y. Kakizawa, T. Kobayashi, Y. Tanaka, K. Seguchi, and K. Hongo Prediction of Functional Outcome in Acute Cerebral Hemorrhage Using Diffusion Tensor Imaging at 3T: A Prospective Study AJNR Am. J. Neuroradiol., September 1, 2009; 30(8): 1561 - 1565. Abstract Full Text PDF Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X

Journal

American Journal of NeuroradiologyAmerican Journal of Neuroradiology

Published: Jun 1, 2008

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