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COMMENTARY Diffusion Tensor Imaging for Predicting the Outcome of Large-Vessel Ischemic Stroke Treated with Mechanical Thrombectomy: Is This the Prime Time? TI uses the physical principles of random displacement of small studies suggests that DTI is suitable for this purpose. Dwater molecules, also known as Brownian motion, to mea- However, there remains a knowledge gap regarding the role of sure the degree and directionality of water molecule motion in DTI in patients with stroke who are treated with mechanical the human body. These measurements can be used to infer the thrombectomy. microstructural integrity of the underlying tissue. In the brain In the article by Berndt et al, the authors aim to answer this healthy WM, cellular membranes, with some contribution from question by addressing the role of DTI in predicting the 3-month myelination and the packing of axons, skew the directionality of functional outcomes of patients with acute ischemic stroke water diffusion, making it less uniform “i.e. anisotropic.” Hence, caused by large-vessel occlusion in the anterior circulation who lower fractional anisotropy (FA) measures have been found to underwent mechanical thrombectomy. The study sample reflect impairment of the WM microstructure. Since its intro- included 165 patients who had DTI sequences
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Feb 1, 2021
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