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ORIGINAL RESEARCH HEAD & NECK Detection of Local Recurrence in Patients with Head and Neck Squamous Cell Carcinoma Using Voxel-Based Color Maps of Initial and Final Area under the Curve Values Derived from DCE-MRI X J.Y. Lee, X K.L. Cheng, X J.H. Lee, X Y.J. Choi, X H.W. Kim, X Y.S. Sung, X S.R. Chung, X K.H. Ryu, X M.S. Chung, X S.Y. Kim, X S.-W. Lee, and X J.H. Baek ABSTRACT BACKGROUNDANDPURPOSE: Early detection of local recurrence is important to increase the chance of cure because local recurrence isthemaincauseoftreatmentfailureinheadandnecksquamouscellcarcinoma.Weevaluatedtheaddedvalueofvoxel-basedcolormaps ofdynamiccontrast-enhancedMRimagingcomparedwithconventionalMRimagingalonefordetectinglocalrecurrenceofheadandneck squamous cell carcinoma. MATERIALS AND METHODS: We retrospectively enrolled 63 consecutive patients with head and neck squamous cell carcinoma after definitive treatment and posttreatment surveillance MR imaging studies that demonstrated focal enhancement at the primary site. Three independent readers assessed conventional MR imaging and a pair of color maps of initial and final 90-second time-signal intensity areas under the curve from dynamic contrast-enhanced MR imaging. The sensitivities, specificities, and accuracies of both conventional MR imaging alone and combined interpretation of conventional and dynamic contrast-enhanced MR imaging statistics were used to evaluate interreader were assessed using the clinicopathologic diagnosis as the criterion standard. agreement. RESULTS: There were 28 patients
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Aug 1, 2019
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