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Cerebral Vasospasm var callbackToken='4736069921AAE12'; American Journal of Neuroradiology Skip to main page content Home Current Issue Publication Preview Search the AJNR Archives Interventional Neuroradiology Neurographics Help Search for Keyword: GO Advanced Search Institution: Deep Dyve User Name Password Sign In Book Review <h2>Cerebral Vasospasm</h2> R.W. Seiler and H.J. Steiger, eds; Vienna: Acta Neurochirurgica, Supplement 77; 2001. 269 pages. 90 illustrations. Price: $105.85. Cerebral vasospasm is a major cause of disability and death associated with subarachnoid hemorrhage. The International Cooperative Study on the Timing of Aneurysm Surgery (1980–1983) showed that clinical vasospasm affected 13.5% of patients with subarachnoid hemorrhage and was responsible for 33% of the occurrences of disability and death in patients with subarachnoid hemorrhage. The introduction of triple-H-therapy (hypervolemia, hemodilution, and hypertension) in the late 1980s helped to reduce ischemic brain damage; however, complications such as hemorrhagic transformation of the ischemic brain tissue, myocardial infarct, and pulmonary edema remain as major limitations. Interventions such as clot lysis, cisternal irrigation with urokinase, neuroprotective agents, and percutaneous transluminal angioplasty have been proposed as ways to reduce cerebral ischemic damage. To date, the use of triple-H-therapy and better overall patient management have led to a significant reduction in permanent neurologic
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Jun 1, 2003
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