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LETTERS e read with interest the article by Hirsch et al in the the number needed to treat to compare treatments, they must WJanuary 2020 issue of the American Journal of examinetherapies in similarpopulations with thesamecondition Neuroradiology (AJNR). If their results are valid, vertebral augmen- at thesamestage,using thesamecomparator, time period,and tation would indeed be a highly efficacious medical procedure. outcomes. The implied target population of the article by Hirsch et Unfortunately, given the information presented in their article, one al is patients with vertebral compression fractures who would be cannot conclude that vertebral augmentation conveys as strong a considered appropriate for vertebral augmentation. However, mortality benefit as they state. While we applaud the authors for they included International Classification of Diseases, Ninth highlighting the morbidity and mortality associated with vertebral Revision, Clinical Modification diagnosis codes that would repre- compression fractures, we have serious methodologic concerns that sent patients highly unlikely to undergo augmentation and who draw into question their conclusions. likely have high rates of mortality. For example, code 805.0 refers Our foremost methodologic concern is that it is unclear on to closed cervical fractures, which are not typically treated with ver- which article and/or dataset the analysis for
American Journal of Neuroradiology – American Journal of Neuroradiology
Published: Aug 1, 2020
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