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Addressing Concerns Regarding the Use of Gadolinium in a Standardized MRI Protocol for the Diagnosis and Follow-Up of Multiple Sclerosis

Addressing Concerns Regarding the Use of Gadolinium in a Standardized MRI Protocol for the... LETTERS Addressing Concerns Regarding the Use of Gadolinium in a Standardized MRI Protocol for the Diagnosis and Follow-Up of Multiple Sclerosis he “Consortium of MS Centers Task Force for a Standardized time, the hallmarks for a diagnosis of MS, with the first MR im- TMRI Protocol and Clinical Guidelines for the Diagnosis and aging scan. Early diagnosis is a special circumstance in which gad- Follow-Up of Multiple Sclerosis” recommended the use of brain olinium is indispensable because an early diagnosis leads to early MR imaging with gadolinium for the diagnosis and routine fol- treatment, which helps in preventing disease progression and may low-up of patients with multiple sclerosis. Soon after the publica- improve the patient’s long-term prognosis. tion of these recommendations, we became aware of the concerns There are a number of other clinical circumstances in which regarding gadolinium deposition in the brain. Because the ad- use of GBCA is essential, including following a patient with highly verse health effects of gadolinium deposits in the brains of pa- active disease, when a patient’s condition is rapidly declining and tients are unknown, we believe gadolinium-based contrast agents unexplained, and when there is a high concern regarding an alter- (GBCA) should http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

Addressing Concerns Regarding the Use of Gadolinium in a Standardized MRI Protocol for the Diagnosis and Follow-Up of Multiple Sclerosis

Traboulsee, A.; Li, D.
American Journal of Neuroradiology , Volume 37 (12) – Dec 1, 2016
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Publisher
American Journal of Neuroradiology
Copyright
© 2016 by American Journal of Neuroradiology
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A4943
Publisher site
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Abstract

LETTERS Addressing Concerns Regarding the Use of Gadolinium in a Standardized MRI Protocol for the Diagnosis and Follow-Up of Multiple Sclerosis he “Consortium of MS Centers Task Force for a Standardized time, the hallmarks for a diagnosis of MS, with the first MR im- TMRI Protocol and Clinical Guidelines for the Diagnosis and aging scan. Early diagnosis is a special circumstance in which gad- Follow-Up of Multiple Sclerosis” recommended the use of brain olinium is indispensable because an early diagnosis leads to early MR imaging with gadolinium for the diagnosis and routine fol- treatment, which helps in preventing disease progression and may low-up of patients with multiple sclerosis. Soon after the publica- improve the patient’s long-term prognosis. tion of these recommendations, we became aware of the concerns There are a number of other clinical circumstances in which regarding gadolinium deposition in the brain. Because the ad- use of GBCA is essential, including following a patient with highly verse health effects of gadolinium deposits in the brains of pa- active disease, when a patient’s condition is rapidly declining and tients are unknown, we believe gadolinium-based contrast agents unexplained, and when there is a high concern regarding an alter- (GBCA) should

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Dec 1, 2016

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