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A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy Devices

A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy... This Article Free to Access Figures Only Full Text Full Text (PDF) All Versions of this Article: ajnr.A1991v1 31/9/1741 most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Google Scholar Articles by Kan, I. Articles by Viñuela, F. PubMed PubMed Citation Articles by Kan, I. Articles by Viñuela, F. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 31:1741-1743, October 2010 © 2010 American Society of Neuroradiology INTERVENTIONAL A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy Devices I. Kan a , I. Yuki a , Y. Murayama a , F.A. Viñuela a , R.H. Kim a , H.V. Vinters b and F. Viñuela a a From the Department of Radiological Sciences (I.K., I.Y., Y.M., F.A.V., R.H.K., F.V.) b Division of Interventional Neuroradiology, Section of Neuropathology, and Departments of Pathology and Laboratory Medicine and Neurology (H.V.V), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. Please address correspondence to Issei Kan, MD, Division of Interventional Neuroradiology, Department of Radiological Sciences, UCLA Medical Center and David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095-1721; e-mail: ikan@mednet.ucla.edu SUMMARY: We report the development of a novel technique of thrombus preparation for use in a swine model for evaluation of thrombectomy devices. The experimental thrombus prepared using plain sedimentation showed mechanical stability due to its solid fibrin-rich component. The thrombus also showed histologic similarity to the typical thromboemboli recovered from patients with stroke in the course of therapeutic thrombectomy. This new technique may be beneficial for preclinical evaluation of thrombectomy devices. Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Neuroradiology American Journal of Neuroradiology

A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy Devices

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Publisher
American Journal of Neuroradiology
Copyright
Copyright © 2010 by the American Society of Neuroradiology.
ISSN
0195-6108
eISSN
1936-959X
DOI
10.3174/ajnr.A1991
Publisher site
See Article on Publisher Site

Abstract

This Article Free to Access Figures Only Full Text Full Text (PDF) All Versions of this Article: ajnr.A1991v1 31/9/1741 most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Google Scholar Articles by Kan, I. Articles by Viñuela, F. PubMed PubMed Citation Articles by Kan, I. Articles by Viñuela, F. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 31:1741-1743, October 2010 © 2010 American Society of Neuroradiology INTERVENTIONAL A Novel Method of Thrombus Preparation for Use in a Swine Model for Evaluation of Thrombectomy Devices I. Kan a , I. Yuki a , Y. Murayama a , F.A. Viñuela a , R.H. Kim a , H.V. Vinters b and F. Viñuela a a From the Department of Radiological Sciences (I.K., I.Y., Y.M., F.A.V., R.H.K., F.V.) b Division of Interventional Neuroradiology, Section of Neuropathology, and Departments of Pathology and Laboratory Medicine and Neurology (H.V.V), David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. Please address correspondence to Issei Kan, MD, Division of Interventional Neuroradiology, Department of Radiological Sciences, UCLA Medical Center and David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095-1721; e-mail: ikan@mednet.ucla.edu SUMMARY: We report the development of a novel technique of thrombus preparation for use in a swine model for evaluation of thrombectomy devices. The experimental thrombus prepared using plain sedimentation showed mechanical stability due to its solid fibrin-rich component. The thrombus also showed histologic similarity to the typical thromboemboli recovered from patients with stroke in the course of therapeutic thrombectomy. This new technique may be beneficial for preclinical evaluation of thrombectomy devices. Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X

Journal

American Journal of Neuroradiology – American Journal of Neuroradiology

Published: Oct 1, 2010

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