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The Synthesis of 3,4-Benzpyrene-5-C14 and of 2-Acetylaminofluorene-9-C14

The Synthesis of 3,4-Benzpyrene-5-C14 and of 2-Acetylaminofluorene-9-C14 The syntheses of two radioactive carcinogens of high specific activity are described in detail. 3,4-Benzpyrene-5-C 14 , specific activity 2.8 µc. per milligram, was obtained in over-all yield of 22 per cent, based on barium carbonate. 2-Acetylaminofluorene-9-C 14 , specific activity 4.55 µc. per milligram, was obtained in over-all yield of 50 per cent, based on barium carbonate. * An abstract of part of this report appeared in Cancer Research, 11:255, 1951. This work was supported in part by a grant from the Wisconsin Section of the American Cancer Society. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cancer Research American Association of Cancer Research

The Synthesis of 3,4-Benzpyrene-5-C14 and of 2-Acetylaminofluorene-9-C14

Heidelberger, Charles; Rieke, Helga Straube
Cancer Research , Volume 11 (8): 640 – Aug 1, 1951
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The Synthesis of 3,4-Benzpyrene-5-C14 and of 2-Acetylaminofluorene-9-C14

Heidelberger, Charles; Rieke, Helga Straube
Cancer Research , Volume 11 (8): 640 – Aug 1, 1951

Abstract

The syntheses of two radioactive carcinogens of high specific activity are described in detail. 3,4-Benzpyrene-5-C 14 , specific activity 2.8 µc. per milligram, was obtained in over-all yield of 22 per cent, based on barium carbonate. 2-Acetylaminofluorene-9-C 14 , specific activity 4.55 µc. per milligram, was obtained in over-all yield of 50 per cent, based on barium carbonate. * An abstract of part of this report appeared in Cancer Research, 11:255, 1951. This work was supported in part by a grant from the Wisconsin Section of the American Cancer Society.

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Publisher
American Association of Cancer Research
Copyright
Copyright © 1951 by the American Association for Cancer Research.
ISSN
0008-5472
Publisher site

Abstract

The syntheses of two radioactive carcinogens of high specific activity are described in detail. 3,4-Benzpyrene-5-C 14 , specific activity 2.8 µc. per milligram, was obtained in over-all yield of 22 per cent, based on barium carbonate. 2-Acetylaminofluorene-9-C 14 , specific activity 4.55 µc. per milligram, was obtained in over-all yield of 50 per cent, based on barium carbonate. * An abstract of part of this report appeared in Cancer Research, 11:255, 1951. This work was supported in part by a grant from the Wisconsin Section of the American Cancer Society.

Journal

Cancer Research – American Association of Cancer Research

Published: Aug 1, 1951

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