-
Xiao-Qi
Wang,
P.
Sun,
M.
O'gorman,
T.
Tai,
A.
Paller
(2001)
Epidermal growth factor receptor glycosylation is required for ganglioside GM3 binding and GM3-mediated suppresion of activation
Glycobiology, 11
-
P.
Choong,
A.
Nadesapillai
(2003)
Urokinase plasminogen activator system: a multifunctional role in tumor progression and metastasis.
Clinical orthopaedics and related research, 415 Suppl
-
P.
Sun,
Xiao-Qi
Wang,
Keith
Lopatka,
Suleman
Bangash,
A.
Paller
(2002)
Ganglioside loss promotes survival primarily by activating integrin-linked kinase/Akt without phosphoinositide 3-OH kinase signaling.
The Journal of investigative dermatology, 119 1
-
R.
Bitton,
M.
Guthmann,
M.
Gabri,
Ariel
Carnero,
D.
Alonso,
L.
Fainboim,
D.
Gomez
(2002)
Cancer vaccines: an update with special focus on ganglioside antigens.
Oncology reports, 9 2
-
Xiao-Qi
Wang,
Q.
Yan,
P.
Sun,
Jiwei
Liu,
Linda
Go,
Shauntae
McDaniel,
A.
Paller
(2007)
Suppression of epidermal growth factor receptor signaling by protein kinase C-alpha activation requires CD82, caveolin-1, and ganglioside.
Cancer research, 67 20
-
O.
Kargiotis,
C.
Chetty,
V.
Gogineni,
C.
Gondi,
Sai
Pulukuri,
A.
Kyritsis,
M.
Gujrati,
J.
Klopfenstein,
D.
Dinh,
J.
Rao
(2008)
uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo.
International journal of oncology, 33 5
-
Xiao-Qi
Wang,
P.
Sun,
A.
Paller
(2001)
Inhibition of Integrin-linked Kinase/Protein Kinase B/Akt Signaling
The Journal of Biological Chemistry, 276
-
S.
Hakomori
(2002)
Glycosylation defining cancer malignancy: New wine in an old bottle
Proceedings of the National Academy of Sciences of the United States of America, 99
-
Xiao-Qi
Wang,
P.
Sun,
A.
Paller
(2003)
Ganglioside GM3 Inhibits Matrix Metalloproteinase-9 Activation and Disrupts Its Association with Integrin*
Journal of Biological Chemistry, 278
-
L.
Fernández,
D.
Alonso,
D.
Gomez,
A.
Vázquez
(2003)
Ganglioside-based vaccines and anti-idiotype antibodies for active immunotherapy against cancer
Expert Review of Vaccines, 2
-
W.
Yu,
Jeanette
Kim,
L.
Ossowski
(1997)
Reduction in Surface Urokinase Receptor Forces Malignant Cells into a Protracted State of Dormancy
The Journal of Cell Biology, 137
-
Xiao-Qi
Wang,
P.
Sun,
A.
Paller
(2002)
Ganglioside Induces Caveolin-1 Redistribution and Interaction with the Epidermal Growth Factor Receptor*
The Journal of Biological Chemistry, 277
-
G.
Pluijm,
B.
Sijmons,
H.
Vloedgraven,
C.
Bent,
J.
Drijfhout,
J.
Verheijen,
P.
Quax,
M.
Karperien,
S.
Papapoulos,
C.
Löwik
(2001)
Urokinase-receptor/integrin complexes are functionally involved in adhesion and progression of human breast cancer in vivo.
The American journal of pathology, 159 3
-
M.
Guthmann,
R.
Bitton,
Ariel
Carnero,
M.
Gabri,
G.
Cinat,
L.
Koliren,
D.
Lewi,
L.
Fernández,
D.
Alonso,
D.
Gomez,
L.
Fainboim
(2004)
Active Specific Immunotherapy of Melanoma with a GM3 Ganglioside-Based Vaccine: A Report on Safety and Immunogenicity
Journal of Immunotherapy, 27
-
M.
Guthmann,
M.
Castro,
G.
Cinat,
C.
Venier,
L.
Koliren,
R.
Bitton,
A.
Vázquez,
L.
Fainboim
(2006)
Cellular and Humoral Immune Response to N-Glycolyl-GM3 Elicited by Prolonged Immunotherapy With an Anti-Idiotypic Vaccine in High-Risk and Metastatic Breast Cancer Patients
Journal of Immunotherapy, 29
-
K.
Lloyd,
K.
Furukawa
(1998)
Biosynthesis and functions of gangliosides: recent advances
Glycoconjugate Journal, 15
-
Xiao-Qi
Wang,
P.
Sun,
A.
Paller
(2003)
Ganglioside GM3 Blocks the Activation of Epidermal Growth Factor Receptor Induced by Integrin at Specific Tyrosine Sites*
Journal of Biological Chemistry, 278
-
R.
Chammas,
J.
Sonnenburg,
N.
Watson,
T.
Tai,
M.
Farquhar,
N.
Varki,
A.
Varki
(1999)
De-N-acetyl-gangliosides in humans: unusual subcellular distribution of a novel tumor antigen.
Cancer research, 59 6
-
A.
Stahl,
B.
Mueller
(1994)
Binding of urokinase to its receptor promotes migration and invasion of human melanoma cells in vitro.
Cancer research, 54 11
-
N.
Sidenius,
F.
Blasi
(2003)
The urokinase plasminogen activator system in cancer: Recent advances and implication for prognosis and therapy
Cancer and Metastasis Reviews, 22
-
E.
Hujanen,
Anne
Väisänen,
A.
Zheng,
Karl
Trygdvason,
T.
Turpeenniemi‐Hujanen
(1994)
Modulation of Mr 72,000 and Mr 92,000 type‐IV collagenase (gelatinase A and B) gene expression by interferons alpha and gamma in human melanoma
International Journal of Cancer, 58
-
T.
Tsuchida,
R.
Saxton,
D.
Morton,
R.
Irie
(1989)
Gangliosides of human melanoma
Cancer, 63
-
S.
Birklé,
G.
Zeng,
L.
Gao,
R.
Yu,
J.
Aubry
(2003)
Role of tumor-associated gangliosides in cancer progression.
Biochimie, 85 3-4
-
Xiao-Qi
Wang,
P.
Sun,
A.
Paller
(2005)
Gangliosides inhibit urokinase-type plasminogen activator (uPA)-dependent squamous carcinoma cell migration by preventing uPA receptor/alphabeta integrin/epidermal growth factor receptor interactions.
The Journal of investigative dermatology, 124 4
-
X.
Wang,
Z.
Rahman,
P.
Sun,
E.
Meuillet,
D.
George,
E.
Bremer,
A.
Al-Qamari,
A.
Paller
(2001)
Ganglioside modulates ligand binding to the epidermal growth factor receptor.
The Journal of investigative dermatology, 116 1
-
Chang-Min
Park,
Myung‐Jin
Park,
H.
Kwak,
Hyung‐Chahn
Lee,
Mi-Suk
Kim,
Seung-Hoon
Lee,
I.
Park,
C.
Rhee,
Seokil
Hong
(2006)
Ionizing radiation enhances matrix metalloproteinase-2 secretion and invasion of glioma cells through Src/epidermal growth factor receptor-mediated p38/Akt and phosphatidylinositol 3-kinase/Akt signaling pathways.
Cancer research, 66 17
-
M.
Lens
(2008)
The role of vaccine therapy in the treatment of melanoma
Expert Opinion on Biological Therapy, 8
-
M.
Gabri,
Z.
Mazorra,
Giselle
Ripoll,
C.
Mesa,
L.
Fernández,
D.
Gomez,
D.
Alonso
(2006)
Complete Antitumor Protection by Perioperative Immunization with GM3/VSSP Vaccine in a Preclinical Mouse Melanoma Model
Clinical Cancer Research, 12
-
S.
D'Alessio,
F.
Margheri,
M.
Pucci,
A.
Rosso,
B.
Monia,
M.
Bologna,
C.
Leonetti,
M.
Scarsella,
G.
Zupi,
G.
Fibbi,
M.
Rosso
(2004)
Antisense oligodeoxynucleotides for urokinase‐plasminogen activator receptor have anti‐invasive and anti‐proliferative effects in vitro and inhibit spontaneous metastases of human melanoma in mice
International Journal of Cancer, 110
-
F.
Blasi,
P.
Carmeliet
(2002)
uPAR: a versatile signalling orchestrator
Nature Reviews Molecular Cell Biology, 3
-
P.
Andreasen,
R.
Egelund,
H.
Petersen
(2000)
The plasminogen activation system in tumor growth, invasion, and metastasis
Cellular and Molecular Life Sciences CMLS, 57
-
Xiao-Qi
Wang,
P.
Sun,
A.
Al-Qamari,
T.
Tai,
I.
Kawashima,
A.
Paller
(2001)
Carbohydrate-Carbohydrate Binding of Ganglioside to Integrin α5 Modulates α5β1Function*
The Journal of Biological Chemistry, 276
-
(2004)
Ganglioside GM 3 exerts reciprocal effects on MMP - 9 and MMP - 2 expression in the presence of uPA
-
Pia
Ragno
(2006)
The urokinase receptor: a ligand or a receptor? Story of a sociable molecule
Cellular and Molecular Life Sciences CMLS, 63
-
U.
Krengel,
Lise-Lotte
Olsson,
C.
Martínez,
Ariel
Talavera,
G.
Rojas,
E.
Mier,
J.
Ångström,
E.
Moreno
(2004)
Structure and Molecular Interactions of a Unique Antitumor Antibody Specific for N-Glycolyl GM3*
Journal of Biological Chemistry, 279
-
Liang-sheng
Lu,
Shun‐le
Chen,
Yue‐ying
Gu,
N.
Shen,
C.
Bao,
Y.
Wang,
C.
Yang,
P.
Ye,
Chong-zhao
Yu
(2002)
[Expression of fusion proteins in beta(2)GP I gene-transfected HEp-2 cells and its clinical application].
Zhonghua yi xue za zhi, 82 6
-
Xiao-Qi
Wang,
P.
Sun,
A.
Paller
(2002)
Ganglioside Modulation Regulates Epithelial Cell Adhesion and Spreading via Ganglioside-specific Effects on Signaling*
The Journal of Biological Chemistry, 277
-
H.
Tsao,
M.
Atkins,
A.
Sober
(2004)
Management of cutaneous melanoma.
The New England journal of medicine, 351 10
-
Xiao-Qi
Wang,
P.
Sun,
Linda
Go,
Viola
Koti,
Margarita
Fliman,
A.
Paller
(2006)
Ganglioside GM3 promotes carcinoma cell proliferation via urokinase plasminogen activator-induced extracellular signal-regulated kinase-independent p70S6 kinase signaling.
The Journal of investigative dermatology, 126 12
-
R.
Irie,
D.
Ollila,
S.
O'Day,
D.
Morton
(2004)
Phase I pilot clinical trial of human IgM monoclonal antibody to ganglioside GM3 in patients with metastatic melanoma
Cancer Immunology, Immunotherapy, 53
-
L.
Postovit,
P.
Dutt,
N.
Dourdin,
Min-Ho
Park,
P.
Greer,
C.
Graham,
J.
Elce
(2002)
Calpain is required for MMP-2 and u-PA expression in SV40 large T-antigen-immortalized cells.
Biochemical and biophysical research communications, 297 2
-
M.
Tardif,
J.
Coulombe,
D.
Soulières,
A.
Rousseau,
G.
Pelletier
(1996)
Gangliosides in human uveal melanoma metastatic process
International Journal of Cancer, 68
-
N.
Hanai,
T.
Dohi,
G.
Nores,
S.
Hakomori
(1988)
A novel ganglioside, de-N-acetyl-GM3 (II3NeuNH2LacCer), acting as a strong promoter for epidermal growth factor receptor kinase and as a stimulator for cell growth.
The Journal of biological chemistry, 263 13
-
Sandip
Saha,
K.
Mohanty
(2003)
Enhancement of metastatic potential of mouse B16-melanoma cells to lung after treatment with gangliosides of B-16-melanoma cells of higher metastatic potential to lung.
Indian journal of experimental biology, 41 11
-
Qianli
Wang,
Junping
Zhang,
Zhongwu
Guo
(2007)
Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell.
Bioorganic & medicinal chemistry, 15 24
-
A.
Hess,
E.
Seftor,
Richard
Seftor,
M.
Hendrix
(2003)
Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.
Cancer research, 63 16
-
Shauntae
McDaniel,
Caitlin
O'neill,
R.
Metz,
Elizabeth
Tarbutton,
M.
Stacewicz‐Sapuntzakis,
J.
Heimendinger,
P.
Wolfe,
H.
Thompson,
P.
Schedin
(2007)
Whole-food sources of vitamin A more effectively inhibit female rat sexual maturation, mammary gland development, and mammary carcinogenesis than retinyl palmitate.
The Journal of nutrition, 137 6
-
S.
Saha,
K.
Mohanty
(2003)
Correlation of gangliosides GM2 and GM3 with metastatic potential to lungs of mouse B16 melanoma.
Journal of experimental & clinical cancer research : CR, 22 1
-
S.
Hakomori
(1990)
Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions.
The Journal of biological chemistry, 265 31
-
A.
Carr,
A.
Mullet,
Z.
Mazorra,
A.
Vázquez,
M.
Alfonso,
C.
Mesa,
E.
Rengifo,
R.
Pérez,
L.
Fernández
(2000)
A mouse IgG1 monoclonal antibody specific for N-glycolyl GM3 ganglioside recognized breast and melanoma tumors.
Hybridoma, 19 3
-
K.
Almholt,
L.
Lund,
J.
Rygaard,
B.
Nielsen,
K.
Danø,
J.
Rømer,
M.
Johnsen
(2005)
Reduced metastasis of transgenic mammary cancer in urokinase‐deficient mice
International Journal of Cancer, 113