Population Distribution of High-Sensitivity C-reactive Protein among US Men: Findings from National Health and Nutrition Examination Survey 1999–2000 Earl S. Ford 1 , a , Wayne H. Giles 2 , Gary L. Myers 3 and David M. Mannino 1 Divisions of 1 Environmental Hazards and Health Effects and 3 Laboratory Sciences, National Center for Environmental Health, and 2 Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341 ↵ a address correspondence to this author at: Centers for Disease Control and Prevention, 4770 Buford Hwy., MS K66, Atlanta, GA 30341; fax 770-488-8150, e-mail firstname.lastname@example.org C-reactive protein, an acute-phase reactant, is produced in the liver and belongs to the pentraxin family of proteins ( 1 ). This protein is very sensitive to inflammation, and its concentration can increase rapidly in response to a wide range of stimuli. Originally described in 1930 ( 2 ), C-reactive protein measurements served mostly in a diagnostic, albeit a nonspecific one, and in a monitoring role in such fields as infectious diseases and rheumatology. In the past decade, as the role of inflammation in cardiovascular disease became appreciated, interest turned
Clinical Chemistry – American Association for Clinical Chemistry
Published: Apr 1, 2003
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