-
S.
Steiniger,
J.
Kreuter,
A.
Khalansky,
I.
Skidan,
A.
Bobruskin,
Z.
Smirnova,
S.
Severin,
R.
Uhl,
M.
Kock,
K.
Geiger,
S.
Gelperina
(2004)
Chemotherapy of glioblastoma in rats using doxorubicin‐loaded nanoparticles
International Journal of Cancer, 109
-
R.
Pitas,
J.
Boyles,
S.
Lee,
D.
Hui,
K.
Weisgraber
(1987)
Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.
The Journal of biological chemistry, 262 29
-
R.
Kotchetkov,
P.
Driever,
J.
Činátl,
M.
Michaelis,
J.
Karásková,
R.
Blaheta,
J.
Squire,
A.
Deimling,
Jussi
Moog,
J.
Cinatl
(2005)
Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on P-gp expression.
International journal of oncology, 27 4
-
M.
Hoffmann,
H.
Scharnagl,
E.
Panagiotou,
W.
Banghard,
H.
Wieland,
W.
März
(2001)
Diminished LDL receptor and high heparin binding of apolipoprotein E2 Sendai associated with lipoprotein glomerulopathy.
Journal of the American Society of Nephrology : JASN, 12 3
-
C.
Weber,
C.
Coester,
Joerg
Kreuter,
Klaus
Langer
(2000)
Desolvation process and surface characterisation of protein nanoparticles.
International journal of pharmaceutics, 194 1
-
E.
Vasile,
M.
Simionescu,
N.
Simionescu
(1983)
Visualization of the binding, endocytosis, and transcytosis of low- density lipoprotein in the arterial endothelium in situ
The Journal of Cell Biology, 96
-
S.
Méresse,
C.
Delbart,
J.
Fruchart,
R.
Cecchelli
(1989)
Low‐Density Lipoprotein Receptor on Endothelium of Brain Capillaries
Journal of Neurochemistry, 53
-
W.
Schneider,
P.
Kovanen,
M.
Brown,
J.
Goldstein,
G.
Utermann,
W.
Weber,
R.
Havel,
L.
Kotite,
J.
Kane,
T.
Innerarity,
R.
Mahley
(1981)
Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows.
The Journal of clinical investigation, 68 4
-
R.
Alyautdin,
V.
Petrov,
K.
Langer,
A.
Berthold,
D.
Kharkevich,
J.
Kreuter
(1997)
Delivery of Loperamide Across the Blood-Brain Barrier with Polysorbate 80-Coated Polybutylcyanoacrylate Nanoparticles
Pharmaceutical Research, 14
-
Address correspondence to: Klaus Langer, Institute for Pharmaceutical Technology, Biocenter of Johann Wolfgang Goethe-University, Marie-Curie- Strasse 9, D-60439 Frankfurt
-
K.
Weisgraber
(1994)
Apolipoprotein E: structure-function relationships.
Advances in protein chemistry, 45
-
H.
Gelderblom,
J.
Verweij,
K.
Nooter,
A.
Sparreboom
(2001)
Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation.
European journal of cancer, 37 13
-
G.
Kolovou,
D.
Daskalova,
D.
Mikhailidis
(2003)
Apolipoprotein E Polymorphism and Atherosclerosis
Angiology, 54
-
Varma
Rk,
R.
Kaushal,
A.
Junnarkar,
G.
Thomas,
M.
Naidu,
Singh
Pp,
R.
Tripathi,
Shridhar
Dr
(1985)
Polysorbate 80: a pharmacological study.
Arzneimittel-Forschung, 35 5
-
L.
Dong,
S.
Parkin,
S.
Trakhanov,
B.
Rupp,
T.
Simmons,
K.
Arnold,
Y.
Newhouse,
T.
Innerarity,
K.
Weisgraber
(1996)
Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia
Nature Structural Biology, 3
-
J.
Ribalta,
J.
Vallvé,
J.
Girona,
L.
Masana
(2003)
Apolipoprotein and apolipoprotein receptor genes, blood lipids and disease
Current Opinion in Clinical Nutrition and Metabolic Care, 6
-
D.
Geselowitz,
L.
Neckers
(1995)
Bovine serum albumin is a major oligonucleotide-binding protein found on the surface of cultured cells.
Antisense research and development, 5 3
-
Sabine
Balthasar,
Kerstin
Michaelis,
N.
Dinauer,
H.
Briesen,
J.
Kreuter,
K.
Langer
(2005)
Preparation and characterisation of antibody modified gelatin nanoparticles as drug carrier system for uptake in lymphocytes.
Biomaterials, 26 15
-
H.
Loof,
M.
Rosseneu,
R.
Brasseur,
J.
Ruysschaert
(1986)
Use of hydrophobicity profiles to predict receptor binding domains on apolipoprotein E and the low density lipoprotein apolipoprotein B-E receptor.
Proceedings of the National Academy of Sciences of the United States of America, 83 8
-
Klaus
Langer,
C.
Coester,
C.
Weber,
H.
Briesen,
Jörg
Kreuter
(2000)
Preparation of avidin-labeled protein nanoparticles as carriers for biotinylated peptide nucleic acid.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 49 3
-
Heidrun
Wartlick,
Kerstin
Michaelis,
Sabine
Balthasar,
K.
Strebhardt,
J.
Kreuter,
K.
Langer
(2004)
Highly Specific HER2-mediated Cellular Uptake of Antibody-modified Nanoparticles in Tumour Cells
Journal of Drug Targeting, 12
-
E.
Corder,
A.
Saunders,
W.
Strittmatter,
D.
Schmechel,
P.
Gaskell,
G.
Small,
A.
Roses,
J.
Haines,
M.
Pericak-Vance
(1993)
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
Science, 261 5123
-
R.
Alyautdin,
E.
Tezikov,
P.
Ramge,
D.
Kharkevich,
David
Begley,
J.
Kreuter
(1998)
Significant entry of tubocurarine into the brain of rats by adsorption to polysorbate 80-coated polybutylcyanoacrylate nanoparticles: an in situ brain perfusion study.
Journal of microencapsulation, 15 1
-
J.
Kreuter
(2004)
Influence of the surface properties on nanoparticle-mediated transport of drugs to the brain.
Journal of nanoscience and nanotechnology, 4 5
-
J.
Nimpf,
W.
Schneider
(2000)
From cholesterol transport to signal transduction: low density lipoprotein receptor, very low density lipoprotein receptor, and apolipoprotein E receptor-2.
Biochimica et biophysica acta, 1529 1-3
-
Z.
Ji,
S.
Fazio,
R.
Mahley,
R.
Mahley
(1994)
Variable heparan sulfate proteoglycan binding of apolipoprotein E variants may modulate the expression of type III hyperlipoproteinemia.
The Journal of biological chemistry, 269 18
-
D.
DeHaven-Hudkins,
Burgos
Lc,
Cassel
Ja,
J.
Daubert,
R.
Dehaven,
E.
Mansson,
H.
Nagasaka,
G.
Yu,
T.
Yaksh
(1999)
Loperamide (ADL 2-1294), an opioid antihyperalgesic agent with peripheral selectivity.
The Journal of pharmacology and experimental therapeutics, 289 1
-
A.
Dergunov
(2004)
Apolipoprotein E Structure and Substrate and Receptor-Binding Activities of Triglyceride-Rich Human Plasma Lipoproteins in Normo- and Hypertriglyceridemia
Biochemistry (Moscow), 69
-
K.
Langer,
Sabine
Balthasar,
V.
Vogel,
N.
Dinauer,
H.
Briesen,
D.
Schubert
(2003)
Optimization of the preparation process for human serum albumin (HSA) nanoparticles.
International journal of pharmaceutics, 257 1-2
-
M.
Michaelis,
I.
Fichtner,
D.
Behrens,
W.
Haider,
F.
Rothweiler,
A.
Mack,
J.
Činátl,
H.
Doerr,
J.
Cinatl
(2006)
Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo.
International journal of oncology, 28 2
-
J.
Kreuter,
D.
Shamenkov,
V.
Petrov,
P.
Ramge,
Klaus
Cychutek,
C.
Koch-Brandt,
R.
Alyautdin
(2002)
Apolipoprotein-mediated Transport of Nanoparticle-bound Drugs Across the Blood-Brain Barrier
Journal of Drug Targeting, 10
-
J.
Kreuter,
R.
Alyautdin,
D.
Kharkevich,
A.
Ivanov
(1995)
Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)
Brain Research, 674
-
Johnny
Croy,
T.
Brandon,
E.
Komives
(2004)
Two apolipoprotein E mimetic peptides, ApoE(130-149) and ApoE(141-155)2, bind to LRP1.
Biochemistry, 43 23
-
M.
Lucarelli,
V.
Borrelli,
A.
Fiori,
A.
Cucina,
F.
Granata,
R.
Potenza,
S.
Scarpa,
A.
Cavallaro,
R.
Strom
(2002)
The expression of native and oxidized LDL receptors in brain microvessels is specifically enhanced by astrocytes‐derived soluble factor(s)
FEBS Letters, 522
-
H.
Chen,
F.
Gaul,
D.
Guo,
A.
Maycock
(2000)
Determination of loperamide in rat plasma and bovine serum albumin by LC.
Journal of pharmaceutical and biomedical analysis, 22 3
-
C.
Weber,
S.
Reiß,
Klaus
Langer
(2000)
Preparation of surface modified protein nanoparticles by introduction of sulfhydryl groups.
International journal of pharmaceutics, 211 1-2
-
G.
Isabel,
D.
Wright,
J.
Henry
(1981)
Design for an inexpensive unit for measuring tail flick latencies.
Journal of pharmacological methods, 5 3
-
B.
Dehouck,
L.
Fenart,
M.
Dehouck,
A.
Pierce,
G.
Torpier,
R.
Cecchelli
(1997)
A New Function for the LDL Receptor: Transcytosis of LDL across the Blood–Brain Barrier
The Journal of Cell Biology, 138
-
Greene
Nm
(1990)
Avidin and streptavidin.
Methods in Enzymology, 184
-
R.
Kotchetkov,
J.
Činátl,
R.
Blaheta,
J.
Vogel,
J.
Karásková,
J.
Squire,
P.
Driever,
T.
Klingebiel,
J.
Cinatl
(2003)
Development of resistance to vincristine and doxorubicin in neuroblastoma alters malignant properties and induces additional karyotype changes: A preclinical model
International Journal of Cancer, 104