TY - JOUR
AU1 - Lord, Rachel
AU2 - Utomi, Victor
AU3 - Oxborough, David
AU4 - Curry, Bryony
AU5 - Brown, Megan
AU6 - George, Keith
AB - Background The cardiac consequences of undertaking endurance exercise are the topic of recent debate. The purpose of this review is to provide an update on a growing body of literature, focusing on left ventricular (LV) function following prolonged endurance exercise over 2 h in duration which have employed novel techniques, including myocardial speckle tracking, to provide a more comprehensive global and regional assessment of LV mechanics. Methods Prospective studies were filtered independently following a pre-set criteria, resulting in the inclusion of 27 studies in the analyses. A random-effects meta-analysis was used to determine the weighted mean difference and 95% confidence intervals (CI) of LV functional and mechanical data from pre-to-post-exercise. Narrative commentary was also provided where volume of available evidence precluded meta-analysis. Results A significant overall reduction in LV longitudinal strain (Ɛ ) n = 22 (− 18 ± 1 to − 17 ± 1%; effect size (d ) − 9: − 1 to − 0.5%), strain rate n = 10 (SR; d − 0.9: − 0.1.3 to − 0.5 l/s) and twist n = 5 (11.9 ± 2.2 to 8.7 ± 2.2°, d − 1: − 1.6 to − 0.3°) was observed following strenuous endurance exercise (range 120–1740 min) (P < 
TI - Left ventricular function and mechanics following prolonged endurance exercise: an update and meta-analysis with insights from novel techniques
JF - European Journal of Applied Physiology
DO - 10.1007/s00421-018-3906-z
DA - 2018-06-05
UR - https://www.deepdyve.com/lp/springer-journals/left-ventricular-function-and-mechanics-following-prolonged-endurance-vteFNuiPIn
SP - 1291
EP - 1299
VL - 118
IS - 7
DP - DeepDyve