TY - JOUR
AU1 - Millán, J.
AU2 - Senra, A.
AU3 - Lorenzo, A.
AU4 - Romero, J.
AU5 - Rodriguez, P.
AU6 - Gallurt, P.
AB - The two major antiproteases (alpha-1-antitrypsin and alpha-2-macroglobulin) were studied in the serum of cancer patients (273 and 103 subjects, respectively) and in a control group. In cancer patients, the values were stratified by clinical stage (local, loco-regional and metastatic disease). Serum alpha-1-antitrypsin was different in normal people (341 ± 110.7 mg/dl) than in every cancer group (p < 0.0005). The behavior of alpha-2-macroglobulin was similar, with significant differences (p < 0.0005) between normal people (317.6 ± 105.4 mg/dl) and the cancer groups. Serum alpha-1-antitrypsin was different in local, loco-regional and metastatic disease; however, alpha-2-macroglobulin did not show these differences. In metastatic disease, sensitivity was 96.66% for alpha-1-antitrypsin and 94.79% for alpha-2-macroglobulin.
TI - Biological Changes in Serum Antiproteases as Related to Tumor Progression
JF - Tumor Biology
DO - 10.1159/000217541
DA - 1988-01-01
UR - https://www.deepdyve.com/lp/karger/biological-changes-in-serum-antiproteases-as-related-to-tumor-rXlq85vaZe
SP - 15
EP - 20
VL - 9
IS - 1
DP - DeepDyve
ER -