TY - JOUR AU1 - Hanaoka, Takaomi AU2 - Kurai, Makoto AU3 - Okada, Mitsuyo AU4 - Ishizone, Satoshi AU5 - Karasawa, Fumitoshi AU6 - Iizuka, Akira AB - Backgrounds Chest low-dose CT screening (LDCTS) has been finding unprecedented numbers of peripheral non- small cell lung cancers (NSCLC) at an early stage and increased the number of patients with surgical indication. It is important to explore the influence of preoperative watchful–waiting time (WWT) on surgical outcomes. Objective is to clarify relationship between WWT and surgical outcomes of LDCTS-finding NSCLC from the view point of treatment delay. Methods Total 283 cases of NSCLC, found by LDCTS and consecutively resected, were surveyed for preoperative WWT and surgical outcomes. Validity of the present guideline for management of pulmonary nodules detected by LDCTS was verified whether WWT before surgery was suitable for eradication of NSCLC. Results The median value of WWT was 4.0 months in total, and the distribution of WWT exhibited long-tail-type pattern. That was 5.0 months in the group of pure ground-glass nodule (pGGN), 4.0 months in the group of part-solid nodule (PSN), and 1.7 months in the group of solid nodule (SON). During long-term postoperative observation time (median 79 months), 10-year progression-free survival rates were 100% in pGGN, 96% in PSN, and 72% in SON (P \ .0001). They decreased significantly depending on enlargement of size: 91% or higher TI - Preoperative Watchful–Waiting Time and Surgical Outcome of Patients with Non-small Cell Lung Cancer Found by Chest Low-Dose CT Screening JF - World Journal of Surgery DO - 10.1007/s00268-017-4439-z DA - 2018-02-28 UR - https://www.deepdyve.com/lp/springer-journals/preoperative-watchful-waiting-time-and-surgical-outcome-of-patients-oZzgto8VWB SP - 2164 EP - 2172 VL - 42 IS - 7 DP - DeepDyve ER -