TY - JOUR AU1 - Vallat, J. M. AU2 - Dunoyer, J. AB - Abstract To the Editor.— We read with interest the letter by E. W. Massey, MD,1 in the March 1978 issue of the Archives, which pointed out the familial occurrence of meralgia paraesthetica. It seems that other entrapment neuropathies, such as carpal tunnel syndrome, can also be familial.We recently reviewed the case of a 53-year-old woman complaining of nocturnal numbness and tingling in the hands. Both carpel tunnels were decompressed surgically, and the symptoms were alleviated. At operation, the median nerves were seen to be constricted under thickened transverse carpal ligaments. Later it was discovered that the patient's father had similar bilateral signs with weakness and wasting of the abductor pollicis brevis muscles. At operation, the same constrictions as in the daughter's case were found. Ultrastructural examination of the ligaments showed collagenous connective tissue without any evidence of amyloid.The reports of Rukavina et al2 and Malhoudji et References 1. Massey EW: Familial occurrence of meralgia paraesthetica . Arch Neurol 35:182, 1978.Crossref 2. Rukavina JG, Block WD, Jackson CE, et al: Primary systemic amyloidosis . Medicine 35:239-334, 1956.Crossref 3. Malhoudji M, Teasdall RD, Adamkiewicz JJ: The genetic amyloidosis with particular references to hereditary neuropathy amyloidosis type II . Medicine 48:1-37, 1939. 4. Danta G: Familial carpal tunnel syndrome with onset in childhood . J Neurol Neurosurg Psychiatry 38:350-355, 1971.Crossref TI - Familial Occurrence of Entrapment Neuropathies JF - Archives of Neurology DO - 10.1001/archneur.1979.00500410101026 DA - 1979-05-01 UR - https://www.deepdyve.com/lp/american-medical-association/familial-occurrence-of-entrapment-neuropathies-mgPqJmLe1B SP - 323 EP - 323 VL - 36 IS - 5 DP - DeepDyve ER -