TY - JOUR AU1 - Wang, Huan AU2 - Tang, Lei AU3 - Wei, Hongling AU4 - Lu, Junkai AU5 - Mu, Changkao AU6 - Wang, Chunlin AB - Background: Scylla paramamosain (Crustacea: Decapoda: Portunidae: Syclla De Hann) is a commercially important mud crab distributed along the coast of southern China and other Indo-Pacific countries (Lin Z, Hao M, Zhu D, et al, Comp Biochem Physiol B Biochem Mol Biol 208-209:29–37, 2017; Walton ME, Vay LL, Lebata JH, et al, Estuar Coast Shelf Sci 66(3–4):493–500, 2006; Wang Z, Sun B, Zhu F, Fish Shellfish Immunol 67:612–9, 2017). While S. paramamosain is a euryhaline species, a sudden drop in salinity induces a negative impact on growth, molting, and reproduction, and may even cause death. The mechanism of osmotic regulation of marine crustaceans has been recently under investigation. However, the mechanism of adapting to a sudden drop in salinity has not been reported. Methods: In this study, transcriptomics analysis was conducted on the gills of S. paramamosain to test its adaptive capabilities over 120 h with a sudden drop in salinity from 23 ‰ to 3 ‰. Results: At the level of transcription, 135 DEGs (108 up-regulated and 27 down-regulated) annotated by NCBI non-redundant (nr) protein database were screened. GO analysis showed that the catalytic activity category showed the most participating genes in the 24 s-tier GO terms, indicating that TI - Transcriptomic analysis of adaptive mechanisms in response to sudden salinity drop in the mud crab, Scylla paramamosain JF - BMC Genomics DO - 10.1186/s12864-018-4803-x DA - 2018-05-31 UR - https://www.deepdyve.com/lp/springer-journals/transcriptomic-analysis-of-adaptive-mechanisms-in-response-to-sudden-cwpi1jjSX8 SP - 1 EP - 12 VL - 19 IS - 1 DP - DeepDyve ER -